Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Human molecular genetics"
DOI: 10.1093/hmg/ddz246
Abstract: Metabolites are small intermediate products of cellular metabolism perturbed in a variety of complex disorders. Identifying genetic markers associated with metabolite concentrations could delineate disease-related metabolic pathways in humans. We tested genetic variants for associations… read more here.
Keywords: metabolic roles; suggest new; chinese suggest; new metabolic ... See more keywords
The new metabolic needs of hematopoietic stem cells.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in hematology"
DOI: 10.1097/moh.0000000000000719
Abstract: PURPOSE OF REVIEW Hematopoietic stem cells (HSCs) are endowed with high regenerative potential to supply mature blood cells throughout life, under steady state or stress conditions. HSCs are thought to rely on glycolysis when in… read more here.
Keywords: new metabolic; needs hematopoietic; hematopoietic stem; metabolic needs ... See more keywords
Metabolomics reveals new metabolic perturbations in children with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Diabetes"
DOI: 10.1111/pedi.12524
Abstract: Using an untargeted metabolomics approach we investigated the metabolome of children with type 1 diabetes (T1D) in comparison with healthy peers and explored the contribution of HbA1c and clinical features to the observed difference. read more here.
Keywords: metabolomics reveals; type diabetes; new metabolic; reveals new ... See more keywords
A new metabolic model of Drosophila melanogaster and the integrative analysis of Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201695
Abstract: The reconstruction of a comprehensive and literature-curated Drosophila metabolic model, iDrosophila1, provided a powerful platform for studying metabolism with systems medicine perspective. read more here.
Keywords: model drosophila; new metabolic; model; melanogaster integrative ... See more keywords