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   Articles with "new mouse" as a keyword



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Late Cognitive Consequences of Gestational Diabetes to the Offspring, in a New Mouse Model

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recommendations! Published in 2019 at "Molecular Neurobiology"

DOI: 10.1007/s12035-019-1624-0

Abstract: Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during gestation, which affects approximately 10% of pregnant women. Although previously considered a transient condition with few long-term consequences, growing evidence suggest that GD… read more here.

Keywords: gestational diabetes; late cognitive; mouse model; new mouse ... See more keywords

Abstract 4077: A new mouse model of gastric adenocarcinoma: A valuable tool for preclinical studies

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recommendations! Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-4077

Abstract: We recently generated the first model of metastatic mixed-type gastric adenocarcinoma that closely recapitulates the human disease. Our model combines conditional loss of E-cadherin (Cdh1fl/fl) and p53 (Trp53fl/fl) with oncogenic Kras (KrasLSL-G12D/+) activation and yellow… read more here.

Keywords: gastric adenocarcinoma; model; new mouse; cancer ... See more keywords

Abstract 7230: New mouse strains NSG-SGM3xIL15xDKO and NSG- FLT3LxDKO are superior to NSG-MHC I/II DKO mice for humanization of peripheral blood mononuclear cells

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recommendations! Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-7230

Abstract: Peripheral blood mononuclear cells (PBMC)-humanized mice serve as important platforms to evaluate efficacy and toxicity. NSG-MHC I/II double-knock out (DKO) mice have been widely used due to being a humanized T cell model with delayed… read more here.

Keywords: mice; dko; sdko fdko; dko mice ... See more keywords

Pathological manifestations of Farber disease in a new mouse model

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recommendations! Published in 2018 at "Biological Chemistry"

DOI: 10.1515/hsz-2018-0170

Abstract: Abstract Farber disease (FD) is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments are clinically available and affected patients have a severely shortened lifespan. Due to the… read more here.

Keywords: mouse model; new mouse; mouse; farber disease ... See more keywords

Soluble Fc Receptor for IgM in Sera From Subsets of Patients With Chronic Lymphocytic Leukemia as Determined by a New Mouse Monoclonal Antibody

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.863895

Abstract: The FcR for IgM (FcµR) is the newest member of the FcR family, selectively expressed by lymphocytes, and distinct from FcRs for switched Ig isotypes that are expressed by various immune cell types and non-hematopoietic… read more here.

Keywords: solfc; patients chronic; lymphocytic leukemia; igm ... See more keywords