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Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-1624-0
Abstract: Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during gestation, which affects approximately 10% of pregnant women. Although previously considered a transient condition with few long-term consequences, growing evidence suggest that GD…
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Keywords:
gestational diabetes;
late cognitive;
mouse model;
new mouse ... See more keywords
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Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4077
Abstract: We recently generated the first model of metastatic mixed-type gastric adenocarcinoma that closely recapitulates the human disease. Our model combines conditional loss of E-cadherin (Cdh1fl/fl) and p53 (Trp53fl/fl) with oncogenic Kras (KrasLSL-G12D/+) activation and yellow…
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Keywords:
gastric adenocarcinoma;
model;
new mouse;
cancer ... See more keywords
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Published in 2018 at "Biological Chemistry"
DOI: 10.1515/hsz-2018-0170
Abstract: Abstract Farber disease (FD) is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments are clinically available and affected patients have a severely shortened lifespan. Due to the…
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Keywords:
mouse model;
new mouse;
mouse;
farber disease ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.863895
Abstract: The FcR for IgM (FcµR) is the newest member of the FcR family, selectively expressed by lymphocytes, and distinct from FcRs for switched Ig isotypes that are expressed by various immune cell types and non-hematopoietic…
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Keywords:
solfc;
patients chronic;
lymphocytic leukemia;
igm ... See more keywords