A new murine Rpl5(uL18) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2021004658
Abstract: Ribosome dysfunction is implicated in multiple abnormal developmental and disease states in humans. Heterozygous germline mutations in genes encoding ribosomal proteins (RPs) are found in the majority of individuals with Diamond Blackfan anemia (DBA) while… read more here.
Keywords: new murine; rpl5; blackfan anemia; diamond blackfan ... See more keywords