Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies
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DOI: 10.3390/molecules28041897
Abstract: Targeting cancer cells that are highly dependent on the nicotinamide adenine dinucleotide (NAD+) metabolite is a promising therapeutic strategy. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme catalyzing NAD+ production. Despite the high efficacy of several… read more here.
Keywords: anticancer activities; nicotinamide phosphoribosyltransferase; hematological malignancies; nampt inhibitors ... See more keywords