Artificial Metalloenzymes on the Verge of New-to-Nature Metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2017.10.003
Abstract: Residing at the interface of chemistry and biotechnology, artificial metalloenzymes (ArMs) offer an attractive technology to combine the versatile reaction repertoire of transition metal catalysts with the exquisite catalytic features of enzymes. While earlier efforts… read more here.
Keywords: verge new; nature metabolism; chemistry; new nature ... See more keywords
Engineering of new-to-nature halogenated indigo precursors in plants.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2018.02.003
Abstract: Plants are versatile chemists producing a tremendous variety of specialized compounds. Here, we describe the engineering of entirely novel metabolic pathways in planta enabling generation of halogenated indigo precursors as non-natural plant products. Indican (indolyl-β-D-glucopyranoside)… read more here.
Keywords: engineering; new nature; engineering new; halogenated indigo ... See more keywords
A welcome from the new Nature editor
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-05606-y
Abstract: Magdalena Skipper explains what readers can expect from the journal under her stewardship.Magdalena Skipper explains what readers can expect from the journal under her stewardship. read more here.
Keywords: new nature; nature editor; welcome new; nature ... See more keywords
Engineering lanthipeptides by introducing a large variety of RiPP modifications to obtain new-to-nature bioactive peptides.
Sign Up to like & getrecommendations! Published in 2023 at "FEMS microbiology reviews"
DOI: 10.1093/femsre/fuad017
Abstract: Natural bioactive peptide discovery is a challenging and time-consuming process. However, advances in synthetic biology are providing promising new avenues in peptide engineering that allow for the design and production of a large variety of… read more here.
Keywords: large variety; new nature; engineering lanthipeptides; engineering ... See more keywords
Clouded Leopard Optimization: A New Nature-Inspired Optimization Algorithm
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3208700
Abstract: This paper proposes a new nature-inspired metaheuristic algorithm called Clouded Leopard Optimization (CLO), which mimics the natural behavior of clouded leopards in the wild. The fundamental inspiration of CLO is derived from two ways of… read more here.
Keywords: clouded leopard; nature inspired; new nature; leopard optimization ... See more keywords
Directed Biosynthesis of New to Nature Alkaloids in a Heterologous Nicotiana benthamiana Expression Host
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.919443
Abstract: Plants produce a wide variety of pharmacologically active molecules classified as natural products. Derivatization of these natural products can modulate or improve the bioactivity of the parent compound. Unfortunately, chemical derivatization of natural products is… read more here.
Keywords: host; natural products; nicotiana benthamiana; new nature ... See more keywords
nurP28, a New-to-Nature Zein-Derived Peptide, Enhances the Therapeutic Effect of Docetaxel in Breast Cancer Monolayers and Spheroids
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27092824
Abstract: The development of novel cancer therapeutic strategies has garnered increasing interest in cancer research. Among the therapeutic choices, chemosensitizers have shown exciting prospects. Peptides are an attractive alternative among the molecules that may be used… read more here.
Keywords: new nature; monolayers spheroids; breast cancer; cancer ... See more keywords