Engineering new neurons: in vivo reprogramming in mammalian brain and spinal cord
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DOI: 10.1007/s00441-017-2729-2
Abstract: Neurons are postmitotic. Once lost because of injury or degeneration, they do not regenerate in most regions of the mammalian central nervous system. Recent advancements nevertheless clearly reveal that new neurons can be reprogrammed from… read more here.
Keywords: mammalian brain; brain spinal; new neurons; spinal cord ... See more keywords
Debate about birth of new neurons in adult brains extends to Alzheimer’s disease
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DOI: 10.1038/d41586-019-00891-7
Abstract: The surprise finding that neurogenesis drops in diseased brains could throw open a new route to therapies.The surprise finding that neurogenesis drops in diseased brains could throw open a new route to therapies. read more here.
Keywords: birth new; neurons adult; adult brains; brains extends ... See more keywords
Environmental enrichment, new neurons and the neurobiology of individuality
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Neuroscience"
DOI: 10.1038/s41583-019-0120-x
Abstract: Abstract‘Enriched environments’ are a key experimental paradigm to decipher how interactions between genes and environment change the structure and function of the brain across the lifespan of an animal. The regulation of adult hippocampal neurogenesis… read more here.
Keywords: enrichment new; neurons neurobiology; neurobiology individuality; environmental enrichment ... See more keywords
Multifaceted circuit functions of adult-born neurons
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DOI: 10.12688/f1000research.20642.1
Abstract: The dentate gyrus continually produces new neurons throughout life. Behavioral studies in rodents and network models show that new neurons contribute to normal dentate functions, but there are many unanswered questions about how the relatively… read more here.
Keywords: adult born; multifaceted circuit; born neurons; circuit functions ... See more keywords
Adult Hippocampal Neurogenesis and Affective Disorders: New Neurons for Psychic Well-Being
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.594448
Abstract: A paradigm shift in neuroscience was the discovery that new neurons are constantly produced in the adult mammalian brain of several species, including Homo sapiens. These new-born cells are formed in some main neurogenic niches,… read more here.
Keywords: adult; hippocampal neurogenesis; affective disorders; adult hippocampal ... See more keywords