New Phenol Esters for Efficient pH-Controlled Amine Acylation of Peptides, Proteins, and Sepharose Beads in Aqueous Media.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00528
Abstract: This paper describes the discovery, synthesis, and use of novel water-soluble acylation reagents for efficient and selective modification, cross-linking, and labeling of proteins and peptides, as well as for their use in the effective modification… read more here.
Keywords: aqueous media; new phenol; phenol esters; sepharose beads ... See more keywords
Discovery of Dotinurad (FYU-981), a New Phenol Derivative with Highly Potent Uric Acid Lowering Activity.
Sign Up to like & getrecommendations! Published in 2020 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.0c00176
Abstract: To derive new uricosuric agents, novel phenol derivatives were synthesized to overcome the disadvantages of benzbromarone (BBR), attributed by its structural features. Herein, we report the discovery of new phenol derivatives with a 1,1-dioxo-1,2-dihydro-3H-1,3-benzothiazole scaffold.… read more here.
Keywords: uric acid; fyu 981; new phenol; dotinurad fyu ... See more keywords
A new phenol derivative isolated from mangrove-derived fungus Eupenicillium sp. HJ002.
Sign Up to like & getrecommendations! Published in 2020 at "Natural product research"
DOI: 10.1080/14786419.2020.1712388
Abstract: A new phenol derivative, 3-chloro-5-hydroxy-4-methoxyphenylacetic acid methyl ester (1), along with five known compounds methyl 4-hydroxyphenylacetate (2), cytosporone B (3), (R)-striatisporolide A (4), (R)-butanedioic acid (5) and ergosterol (6) were isolated from the mangrove-derived fungus… read more here.
Keywords: mangrove derived; derived fungus; new phenol; isolated mangrove ... See more keywords
Two new phenol compounds from roots of Ardisia crenata.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2064465
Abstract: Two new phenols, ardisiphenol I (1) and ardisiphenol J (2), along with three known compounds (3-5) were isolated and identified from the roots of Ardisia crenata var. bicolor. Their structures were elucidated by means of… read more here.
Keywords: two new; roots ardisia; compounds roots; phenol compounds ... See more keywords