MitoEVs: A new player in multiple disease pathology and treatment
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12320
Abstract: Abstract Mitochondrial damage plays vital roles in the pathology of many diseases, such as cancers, neurodegenerative diseases, aging, metabolic diseases and many types of organ injury. However, the regulatory mechanism of mitochondrial functions among different… read more here.
Keywords: player multiple; disease; pathology; mitoevs ... See more keywords
Glutathione peroxidase 4: a new player in neurodegeneration?
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Psychiatry"
DOI: 10.1038/mp.2016.196
Abstract: Glutathione peroxidase 4 (GPx4) is an antioxidant enzyme reported as an inhibitor of ferroptosis, a recently discovered non-apoptotic form of cell death. This pathway was initially described in cancer cells and has since been identified… read more here.
Keywords: peroxidase new; glutathione peroxidase; neurodegeneration; new player ... See more keywords
A new player contributing to durable Fusarium resistance
Sign Up to like & getrecommendations! Published in 2019 at "Nature Genetics"
DOI: 10.1038/s41588-019-0454-3
Abstract: Fhb1 is the most effective and most widely deployed source of durable resistance against Fusarium graminearum, a devastating toxin-producing fungal pathogen affecting wheat. Two new studies identify Fhb1 as an atypical disease resistance gene; this… read more here.
Keywords: fusarium; durable fusarium; contributing durable; new player ... See more keywords
Identification of Prominin‐2 as a new player of cardiomyocyte senescence in the aging heart
Sign Up to like & getrecommendations! Published in 2024 at "Aging Cell"
DOI: 10.1111/acel.14204
Abstract: The aging heart is characterized by a number of structural changes leading to ventricular stiffness, impaired resistance to stress and increased risk of developing heart failure (HF). Genetic or pharmacological removal of senescent cells has… read more here.
Keywords: senescence; new player; heart; aging heart ... See more keywords
The Arabidopsis thaliana F-box gene HAWAIIAN SKIRT is a new player in the microRNA pathway
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0189788
Abstract: In Arabidopsis, the F-box HAWAIIAN SKIRT (HWS) protein is important for organ growth. Loss of function of HWS exhibits pleiotropic phenotypes including sepal fusion. To dissect the HWS role, we EMS-mutagenized hws-1 seeds and screened… read more here.
Keywords: hws; hawaiian skirt; new player; box ... See more keywords
FOXC1, the new player in the cancer sandbox
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.22742
Abstract: In recent years, rapidly accumulating evidence implicates forkhead box C1 (FOXC1) in cancer, especially in studies of basal-like breast cancer (BLBC). Other studies have followed suit, demonstrating that FOXC1 is not only a major player… read more here.
Keywords: player; foxc1 new; new player; cancer sandbox ... See more keywords
Twist1 activated circRNA-10720 is a new player in hepatocellular carcinoma metastasis
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/26206
Abstract: Epithelial-mesenchymal transition (EMT) is a process that allows an epithelial cell to acquire a mesenchymal-like phenotype that enhances migration capacities. One of the first steps in the EMT process is the loss of cell-cell contacts,… read more here.
Keywords: twist1 activated; 10720 new; activated circrna; new player ... See more keywords
SRGAP2a: A New Player That Modulates Podocyte Cytoskeleton and Injury in Diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes"
DOI: 10.2337/dbi17-0050
Abstract: Podocyte injury and podocyte loss are common features in diabetic kidney disease (DKD). Podocyte detachment and decreased podocyte numbers occur in patients with type 1 or type 2 diabetes and correlate with the progression of… read more here.
Keywords: player modulates; loss; new player; diabetes srgap2a ... See more keywords
Editorial: The Non-Coding Transcriptome as a New Player in Intercellular Communication
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.858702
Abstract: Cardiovascular Research Unit, Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg, Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167 RID-AGE-Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille,… read more here.
Keywords: new player; coding transcriptome; transcriptome new; editorial non ... See more keywords
A new player in circadian networks: Role of electrical synapses in regulating functions of the circadian clock
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.968574
Abstract: Several studies have indicated that coherent circadian rhythms in behaviour can be manifested only when the underlying circadian oscillators function as a well-coupled network. The current literature suggests that circadian pacemaker neuronal networks rely heavily… read more here.
Keywords: electrical synapses; role electrical; circadian networks; player circadian ... See more keywords
Thykamine™: A New Player in the Field of Anti-Inflammatory Drugs
Sign Up to like & getrecommendations! Published in 2025 at "Biomedicines"
DOI: 10.3390/biomedicines13122938
Abstract: Background/Objectives: Persistent inflammation driven by cytokines/chemokines plays a crucial role in the pathogenesis of numerous chronic inflammatory and autoimmune conditions, including rheumatoid arthritis, atopic dermatitis, and ulcerative colitis. Current therapeutic agents often present limitations due… read more here.
Keywords: thykamine; new player; potency; thykamine new ... See more keywords