A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.08.092
Abstract: Dysregulation of the Amyloid Precursor Protein (APP) processing leading to toxic species of amyloid β peptides (Aβ) is central to Alzheimer's disease (AD) etiology. Aβ peptides are produced by sequential cleavage of APP by β-secretase… read more here.
Keywords: precursor protein; indirect secretase; profile indirect; new profile ... See more keywords
The rise of online sports betting, its fallout, and the onset of a new profile in gambling disorder: young people
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Addictive Diseases"
DOI: 10.1080/10550887.2021.1886567
Abstract: Abstract Hypothesis: Since 2015 the gambling trend may have changed among young people between 18 and 30 years old. Methodology: Range of document review techniques obtained by therapeutic data regarding the personal development of each person… read more here.
Keywords: gambling disorder; sports betting; new profile; online sports ... See more keywords