New pyrrolopyridine-based thiazolotriazoles as diabetics inhibitors: enzymatic kinetics and in silico study.
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DOI: 10.4155/fmc-2022-0306
Abstract: Aim: To synthesize pyrrolopyridine-based thiazolotriazoles as a novel class of α-amylase and α-glucosidase inhibitors and to determine their enzymatic kinetics. Methodology: Pyrrolopyridine-based thiazolotriazole analogs (1-24) were synthesized and characterized through proton nuclear magnetic resonance, carbon-13 nuclear magnetic resonance… read more here.
Keywords: pyrrolopyridine based; new pyrrolopyridine; amylase glucosidase; based thiazolotriazoles ... See more keywords