Articles with "new quinazoline" as a keyword



Synthesis and Antibacterial Properties of New Quinazoline Analogs Catalyzed by Chloroacetic Acid–Immobilized Nanocobaltferrite

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Published in 2025 at "Applied Organometallic Chemistry"

DOI: 10.1002/aoc.7969

Abstract: In this research, an effective procedure for the one‐pot construction of new quinazoline analogs using chloroacetic acid–immobolized nanocobaltferrite (nano‐CoFe2O4@SiO2@CPTES‐[(Ph₂PCH₂)₂‐CH2CO2H]2+2Cl−) as an efficient novel magnetic nanocatalyst under ultrasound irradiation at 80°C was presented. Chloroacetic acid–immobilized nanocobferrite… read more here.

Keywords: acid immobilized; new quinazoline; chloroacetic acid; quinazoline analogs ... See more keywords
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Design, synthesis, crystal structure, and antimicrobial activities of new quinazoline derivatives containing both the sulfonate ester and piperidinylamide moieties.

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Published in 2023 at "Pest management science"

DOI: 10.1002/ps.7459

Abstract: BACKGROUND To discover more efficient antimicrobial agents in agriculture, a series of new quinazoline derivatives bearing both sulfonate ester and piperidine-4-carboxamide moieties were synthesized and assessed for their antimicrobial effects. RESULTS All of the target… read more here.

Keywords: sulfonate ester; quinazoline derivatives; compound; new quinazoline ... See more keywords
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Synthesis of new quinazoline-containing hydroxamic acids as potential HDAC/VEGFR inhibitors. Unusual rearrangements with pyrrolidone ring opening and dehydration of 3-N-hydroxyquinazoline fragment containing tetracycles

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Published in 2019 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2019.151315

Abstract: Abstract Synthesis pathways were developed and new hydroxamic acids were obtained as potential inhibitors of HDAC/VEGFR2, including tetracycles containing quinazolinone fragment as a “cap”. Further biological testing of the obtained compounds will give an opportunity… read more here.

Keywords: containing hydroxamic; synthesis new; new quinazoline; hydroxamic acids ... See more keywords

SynthesIs, antiproliferative evaluation and in silico studies of new quinazoline derivatives as VEGFR-2 inhibitors.

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Published in 2025 at "Future medicinal chemistry"

DOI: 10.1080/17568919.2025.2525073

Abstract: BACKGROUND New quinazoline derivatives were designed and synthesized to target VEGFR-2, aiming to identify potential anticancer agents. RESEARCH DESIGN AND METHODS The synthesized compounds underwent in vitro screening to evaluate their cytotoxic effects across 60… read more here.

Keywords: new quinazoline; quinazoline derivatives; vegfr inhibitory; cell ... See more keywords