Introduction of new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives as new α-glucosidase and α-amylase inhibitors
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DOI: 10.1038/s41598-025-16661-7
Abstract: In the present work, new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives 12a-o were assigned as potent anti-diabetic agents that targeting α-glucosidase and α-amylase as two important targets in treatment of type 2 diabetes. General scaffold of these compounds… read more here.
Keywords: amylase; quinolone thio; glucosidase amylase; new quinolone ... See more keywords
A new quinolone and acetylcholinesterase inhibitors from a sponge-associated fungus Penicillium sp. SCSIO41033.
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DOI: 10.1080/14786419.2022.2139694
Abstract: The chemical investigation of the EtOAc extract from the solid rice medium cultured with a sponge-associated fungus Penicillium sp. SCSIO41033 led to the isolation of two quinolones including a new one, penicinolone (1), three xanthone… read more here.
Keywords: new quinolone; associated fungus; penicillium scsio41033; sponge associated ... See more keywords
A New Quinolone Alkaloid with Cytotoxic Activity from the Fruits of Euodia Rutaecarpa
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DOI: 10.1177/1934578x1801300317
Abstract: A new quinolone alkaloid, 1-methyl-2-[(Z)-1-undecenyl]–4(1H)-quinolone (1), together with two known quinolone alkaloids (2–3), and three known limonoids (4–6), were isolated from the fruits of Euodia rutaecarpa (Juss.) Benth.. Their chemical structure was determined by UV,… read more here.
Keywords: euodia rutaecarpa; alkaloid cytotoxic; fruits euodia; quinolone alkaloid ... See more keywords