A New Regioselective Synthesis of the Cysteine-Rich Peptide Linaclotide
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DOI: 10.3390/molecules28031007
Abstract: Linaclotide is a 14-amino acid residue peptide approved by the FDA for the treatment of irritable bowel syndrome with constipation (IBS-C), which activates guanylate cyclase C to accelerate intestinal transit. Here we show a new… read more here.
Keywords: synthesis cysteine; cysteine rich; synthesis; regioselective synthesis ... See more keywords