A New Catalyst for a New Selectivity
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DOI: 10.1016/j.chempr.2020.05.020
Abstract: Download : Download high-res image (123KB) Download : Download full-size image After completing his undergraduate degree at Sheffield Hallam University, during which he undertook extended research projects with Prof. Joseph Harrity (the University of Sheffield)… read more here.
Keywords: new selectivity; catalyst new; research; download ... See more keywords
Structure-Based Discovery of a New Selectivity-Enabling Motif for the FK506-Binding Protein 51.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00249
Abstract: In recent years, the selective inhibition of FKBP51 has emerged as a possible treatment for chronic pain, obesity-induced diabetes, or depression. All currently known advanced FKBP51-selective inhibitors, including the widely used SAFit2, contain a cyclohexyl… read more here.
Keywords: discovery new; based discovery; selectivity; new selectivity ... See more keywords