New structural insights into the oligosaccharide phosphate fraction of Pichia (Hansenula) holstii NRRL Y2448 phosphomannan.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate research"
DOI: 10.1016/j.carres.2017.05.008
Abstract: The oligosaccharide phosphate fraction (OPF) obtained from mild acid hydrolysis of P. holstii NRRL Y-2448 phosphomannan is the starting material for the preparation of the Phase III anticancer drug candidate PI-88. The OPF was for the… read more here.
Keywords: holstii nrrl; phosphate fraction; oligosaccharide phosphate; new structural ... See more keywords
Hexaniobate Cluster Anion Monolayers on Gold Nanoparticles: A New Structural Role for Alkali Metal Countercations.
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b03139
Abstract: Monolayer shells of polyoxotungstate cluster anions on gold nanoparticles in water were electrostatically stabilized by structurally integrated countercations, with formation constants, K, increasing in the order: Li+ < Na+ < K+ < TMA+ < Cs+… read more here.
Keywords: gold nanoparticles; alkali metal; hexaniobate cluster; new structural ... See more keywords
A New Structural Model of Enzymatic Lignin with Multiring Aromatic Clusters
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01812
Abstract: Lignin is a natural aromatic compound in plants. Several lignin structural models have been proposed in the past years, but all the models cannot be converted to benzene carboxylic acids (BCAs) for all aromatic rings… read more here.
Keywords: lignin; aromatic clusters; structural model; new structural ... See more keywords
Biosynthesis and trafficking of heme o and heme a: new structural insights and their implications for reaction mechanisms and prenylated heme transfer
Sign Up to like & getrecommendations! Published in 2021 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2021.1957668
Abstract: Abstract Aerobic respiration is a key energy-producing pathway in many prokaryotes and virtually all eukaryotes. The final step of aerobic respiration is most commonly catalyzed by heme-copper oxidases embedded in the cytoplasmic or mitochondrial membrane.… read more here.
Keywords: biosynthesis; trafficking heme; heme; new structural ... See more keywords
Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2022.2153841
Abstract: Abstract SGK1 is a serine/threonine kinase involved in several neurodegenerative-related pathways such as apoptosis, neuroinflammation, ionic channel regulation, and autophagy, among others. Despite its potential role as a pharmacological target against this kind of diseases,… read more here.
Keywords: identification new; new structural; sgk1 inhibitors; structural family ... See more keywords
New Structural Modifications of Cotarnine Alkaloid Derivatives: Cotarnone and Dihydrocotarnine
Sign Up to like & getrecommendations! Published in 2020 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363220020127
Abstract: Abstract Simplest derivatives of the cotarnine alkaloid, like cotarnone and 1,2-dihydrocotarnine, undergo electrophilic Einhorn acylamidomethylation (with 60–95% yield) and sulfochlorination with chlorosulfonic acid at position 5. At the same time cotarnone and its derivatives undergo… read more here.
Keywords: cotarnone dihydrocotarnine; modifications cotarnine; structural modifications; alkaloid derivatives ... See more keywords
Abstract IA05: Uncovering new structural insights into RAS interactions with effectors and regulators
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras23-ia05
Abstract: RAS proteins, which act as binary molecular switches, are implicated in approximately 20% of all cancer cases and are known to play a critical role in the initiation and progression of some of the deadliest… read more here.
Keywords: structural insights; effectors regulators; ras interactions; new structural ... See more keywords
Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding.
Sign Up to like & getrecommendations! Published in 2018 at "Glycobiology"
DOI: 10.2210/pdb5xrl/pdb
Abstract: Galectin-10 (Gal-10) which forms Charcot-Leyden crystals in vivo, is crucial to regulating lymph cell function. Here, we solved the crystal structures of Gal-10 and eight variants at resolutions of 1.55-2.00 A. Structural analysis and size… read more here.
Keywords: galectin; new structural; dimer; ligand binding ... See more keywords
Research on Tensile Behaviour of New Structural Material MoNiCa
Sign Up to like & getrecommendations! Published in 2019 at "Materials Science"
DOI: 10.5755/j01.ms.25.3.23079
Abstract: This article presents the results of a set of innovative research to analyse a new structural material – steel like austempered ductile cast iron with mechanical properties similar to heat-treated steel, and with technological and… read more here.
Keywords: structural material; new structural; material monica; strength ... See more keywords