A recent update on new synthetic chiral compounds with antileishmanial activity
Sign Up to like & getrecommendations! Published in 2022 at "Chirality"
DOI: 10.1002/chir.23494
Abstract: Abstract Parasitic diseases, including malaria, leishmaniasis, and trypanosomiasis, affect billions of people and are responsible for almost 500,000 deaths/year. In particular, leishmaniasis, a neglected tropical disease, is considered a global public health problem because current… read more here.
Keywords: chiral compounds; new synthetic; activity; update new ... See more keywords
Detection and characterization of the new synthetic cannabinoid APP-BINACA in forensic casework.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2698
Abstract: New psychoactive substances (NPS) continue to emerge around the world. APP-BINACA (or APP-BUTINACA), a novel synthetic cannabinoid, was first reported in Europe in January 2019 and later in the United States in March 2019. APP-BINACA… read more here.
Keywords: app binaca; new synthetic; synthetic cannabinoid; binaca ... See more keywords
Investigation of the μ and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520 and U-48800.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3238
Abstract: In 2009 new synthetic opioids appeared on the new psychoactive substances market. This class of new psychoactive substances generally poses a health risk due to the high affinity and potency of most of these compounds… read more here.
Keywords: opioid receptor; synthetic opioids; using gtp; group ... See more keywords
Case report: relevance of metabolite identification to detect new synthetic opioid intoxications illustrated by U-47700
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-018-1969-3
Abstract: Today, new psychoactive substances (NPS) producers increasingly appear to be targeting new synthetic opioids (NSOs), and the recent emergence of NSOs is causing considerable concern in North America and in Europe. For toxicologists, NSO detection… read more here.
Keywords: case; report relevance; desmethyl 47700; new synthetic ... See more keywords
A New Synthetic Route Towards Picealactone a from an Abietic Acid
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-017-2084-2
Abstract: A new synthetic route towards picealactone A from an abietic acid, dehydroabietic acid, was introduced in this study. In this synthetic route, the picealactone A was synthesized by a tandem oxide/intramolecular esterification of 7-carbonyl dehydroabietic… read more here.
Keywords: synthetic route; route towards; picealactone abietic; new synthetic ... See more keywords
New Synthetic Method and Insecticidal Activities of Novel Imidazopyridine Mesoionic Derivatives Containing an Ester Group.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c05879
Abstract: To develop novel insecticides with high efficiency, a new mode of action, and safety to nontarget organisms and the environment, a series of imidazopyridine mesoionic compounds containing an ester group have been designed and synthesized… read more here.
Keywords: ester group; group; new synthetic; imidazopyridine mesoionic ... See more keywords
New Synthetic Routes to (+)-Uleine and (-)-Tubifolidine: General Approach to 2-Azabicyclo[3.3.1]nonane Indole Alkaloids.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c00912
Abstract: Novel asymmetric synthetic routes to (+)-uleine and (-)-tubifolidine are reported herein. The regioselective formation of enol triflates from 2-azabicyclo[3.3.1]nonane ketones followed by indolizations of the resultant ene-hydrazides allowed the efficient construction of key indole intermediates,… read more here.
Keywords: routes uleine; tubifolidine general; azabicyclo nonane; synthetic routes ... See more keywords
New Synthetic Route to an Highly Efficient Photoredox Catalyst by Mechanosynthesis
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DOI: 10.1021/acsomega.8b01586
Abstract: Photoredox catalysis based on the [Cu(neo)(DPEphos)]BF4 copper complex allowed getting a significant improvement of the polymerization performances (e.g., thick samples, coatings...) compared to that obtained with other benchmarked photoinitiators in both cationic (CP) and free… read more here.
Keywords: synthetic route; mechanosynthesis; copper; photoredox ... See more keywords
New synthetic strategies leading to [RNPNR]- anions and the isolation of the [P(Nt-Bu)3]3- trianion.
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt02141d
Abstract: New and straightforward synthetic paths for the syntheses of [RNPNR]- anions (R = t-Bu (1) or CPh3 (6)) in the form of their tmeda- or thf-coordinated lithium salts are described. The attempts to isolate the… read more here.
Keywords: trianion; rnpnr anions; leading rnpnr; new synthetic ... See more keywords
A comprehensive approach providing a new synthetic route for bimetallic electrocatalysts via isoPOMs [M/Rh(Cp*)4W8O32] (M = Rh (1) and Ir (2)).
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt03227k
Abstract: Polyoxometalates (POMs) are highly versatile materials if paired with various conducting supports. We here present a new prospective approach for obtaining advanced electrocatalytic systems via POMs (1 and 2) nanostructured on Ni foam (NF) to… read more here.
Keywords: synthetic route; comprehensive approach; approach providing; new synthetic ... See more keywords
Black arsenic: a new synthetic method by catalytic crystallization of arsenic glass.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/c9nr09627b
Abstract: Two-dimensional structures of elemental analogues of graphene have received much attention in recent years due to their outstanding properties. Black arsenic is a metastable form of arsenic with an orthorhombic structure similar to black phosphorus.… read more here.
Keywords: black arsenic; method catalytic; crystallization; synthetic method ... See more keywords