The understanding of Parkinson's disease through genetics and new therapies.
Sign Up to like & getrecommendations! Published in 2022 at "Brain and behavior"
DOI: 10.1002/brb3.2577
Abstract: INTRODUCTION Parkinson's disease is one of the progressive neurodegenerative diseases from which people suffer for years. The mechanism of this disease is associated with a decrease in the number of dopaminergic neurons in the substantia… read more here.
Keywords: new therapies; parkinson disease; motor; genetics ... See more keywords
New Therapies for Hypophosphatemia-Related to FGF23 Excess
Sign Up to like & getrecommendations! Published in 2020 at "Calcified Tissue International"
DOI: 10.1007/s00223-020-00705-3
Abstract: FGF23 is a hormone produced by osteocytes in response to an elevation in the concentration of extracellular phosphate. Excess production of FGF23 by bone cells, or rarely by tumors, is the hormonal basis for several… read more here.
Keywords: fgf23; fgf23 mediated; treatment; new therapies ... See more keywords
Reducing the risk of death induced by aluminum phosphide poisoning: The new therapies.
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2022.133800
Abstract: Numerous people suffer from accidental or deliberate exposure to different pesticides when poisoning with aluminum phosphate (AlP) is increasing in the eastern countries. Aluminum phosphate is a conventional insecticide that quickly reacts with water or… read more here.
Keywords: reducing risk; risk death; death induced; aluminum ... See more keywords
Impact of recommendations and new therapies on the prognosis of colon cancer with synchronous liver metastasis.
Sign Up to like & getrecommendations! Published in 2021 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2021.101856
Abstract: OBJECTIVE To assess the prognostic impact of the new therapies recommended over the past twenty years for colonic cancers with synchronous hepatic metastasis (hmCC). METHODS From 1995 to 2016, 802 hmCC were identified in a… read more here.
Keywords: chemotherapy; primary tumor; new therapies; impact recommendations ... See more keywords
Multiple sclerosis in 2018: new therapies and biomarkers
Sign Up to like & getrecommendations! Published in 2019 at "The Lancet Neurology"
DOI: 10.1016/s1474-4422(18)30455-1
Abstract: 2018 has been a year of substantial progress in multiple sclerosis research, with breakthroughs in experimental medicine and translational research. Advances have ranged from successful clinical trials to new reports of promising biomarkers and improved… read more here.
Keywords: new therapies; 2018 new; therapies biomarkers; sclerosis ... See more keywords
New therapies for obesity.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac176
Abstract: Obesity is a chronic disease associated with serious complications and increased mortality. Weight loss through lifestyle changes results in modest weight loss long-term possibly due to compensatory biological adaptations (increased appetite and reduced energy expenditure)… read more here.
Keywords: therapies obesity; weight loss; loss; new therapies ... See more keywords
New therapies for esophageal strictures in children
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001049
Abstract: Purpose of review The present review aims at describing recent advances in therapeutic strategies for the treatment of benign esophageal strictures in children. We discuss current knowledge and practice on esophageal dilations, which are still… read more here.
Keywords: strictures children; new therapies; esophageal strictures; esophageal ... See more keywords
Advancements in therapeutics for inborn errors of metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001168
Abstract: Purpose of review To present new therapeutic modalities for inborn errors of metabolism that are in clinical trials or recently approved by the US Food and Drug Administration (FDA) and to improve pediatricians’ understanding of… read more here.
Keywords: advancements therapeutics; errors metabolism; inborn errors; new therapies ... See more keywords
The Obesity Paradox in Heart Failure: Is It Still Valid in Light of New Therapies?
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology"
DOI: 10.1159/000527332
Abstract: Background: Obesity increases the risk of cardiovascular disease and heart failure (HF). However, in patients with established HF, many studies observed greater survival with increasing adiposity. This counterintuitive observation has been termed the “obesity paradox.”… read more here.
Keywords: obesity; obesity paradox; heart failure; new therapies ... See more keywords
Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0282970
Abstract: Background This systematic review evaluates pneumolysin (PLY) as a target for new treatments against pneumococcal infections. Pneumolysin is one of the main virulence factors produced by all types of pneumococci. This toxin (53 kDa) is… read more here.
Keywords: pneumolysin target; new therapies; systematic review; target new ... See more keywords
New therapies for the treatment of heart failure: a summary of recent accomplishments
Sign Up to like & getrecommendations! Published in 2019 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s179302
Abstract: Despite continuous efforts to prevent cardiovascular diseases (CVDs), heart failure prevails as the number one cause of death in developed countries. To properly treat CVDs, scientists had to take a closer look at the factors… read more here.
Keywords: new therapies; heart; therapies treatment; heart failure ... See more keywords