Electrochemical study of 2-amino-5-mercapto-1,3,4-thiadiazole in the absence and presence of p-benzoquinone: an efficient strategy for the electrosynthesis of new 1,3,4-thiadiazole derivatives
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DOI: 10.1039/d2ra07250e
Abstract: In this study, first, the electrochemical behavior of 2-amino-5-mercapto-1,3,4-thiadiazole (AMT) was fully investigated in the absence and presence of electrochemically generated p-benzoquinone (p-BQ, which is the oxidized form of hydroquinone), as an electrophile, via cyclic… read more here.
Keywords: new thiadiazole; electrosynthesis new; absence presence; mercapto thiadiazole ... See more keywords
Synthesis and Cytotoxic Activity of New 1,3,4-Thiadiazole Thioglycosides and 1,2,3-Triazolyl-1,3,4-Thiadiazole N-glycosides
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DOI: 10.3390/molecules24203738
Abstract: New 1,3,4-thiadiazole thioglycosides linked to substituted arylidine systems were synthesized via glycosylation of the prepared 1,3,4-thiadiazole thiol compounds. Click strategy was also used for the synthesis of new 1,3,4-thiadiazole and 1,2,3-triazole hybrid glycosides by reaction… read more here.
Keywords: synthesis cytotoxic; thiadiazole thioglycosides; new thiadiazole; cytotoxic activity ... See more keywords
New 1,3,4-Thiadiazole Derivatives with Anticancer Activity
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DOI: 10.3390/molecules27061814
Abstract: We designed and synthesized the 1,3,4-thiadiazole derivatives differing in the structure of the substituents in C2 and C5 positions. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and… read more here.
Keywords: cell; new thiadiazole; breast cancer; activity ... See more keywords