Synthesis of New Thiazolo[3,2-b][1,2,4]triazole Derivatives and Preliminary Evaluation of Their Biological Activity
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DOI: 10.1134/s1070363219010067
Abstract: Heterocyclization of 3-[(1H-1,2,4-triazol-3-yl)thio]pentane-2,4-dione afforded 1-(6-methylthiazolo[3,2-b][1,2,4]-triazol-5-yl)ethan-1-one, the reactions of which with hydroxylamine, hydrazincarboxamide, hydrazincarbothioamide, hydrazine hydrate and para-toluenesulfonyl hydrazide resulted in the formation of the corresponding derivatives. 1-(6-Methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethan-1-one oxime reacted with alkyl halides and phenyl isocyanate… read more here.
Keywords: triazole derivatives; derivatives preliminary; new thiazolo; synthesis new ... See more keywords