Articles with "new thienopyridinium" as a keyword



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Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14040715

Abstract: Due to its role in lipid biosynthesis, choline kinase α1 (CKα1) is an interesting target for the development of new antitumor agents. In this work, we present a series of 41 compounds designed based on… read more here.

Keywords: choline kinase; evaluation new; biological evaluation; kinase ... See more keywords