To add or not to add a new treatment arm to a multiarm study: A decision‐theoretic framework
Sign Up to like & getrecommendations! Published in 2019 at "Statistics in Medicine"
DOI: 10.1002/sim.8194
Abstract: Multiarm clinical trials, which compare several experimental treatments against control, are frequently recommended due to their efficiency gain. In practise, all potential treatments may not be ready to be tested in a phase II/III trial… read more here.
Keywords: trial; treatment; add new; study ... See more keywords
Invited Response on: A New Treatment for Local Adiposity With Ascorbic Acid and Ascorbyl-palmitate Solution: Clinical and Histological Study
Sign Up to like & getrecommendations! Published in 2021 at "Aesthetic Plastic Surgery"
DOI: 10.1007/s00266-021-02480-4
Abstract: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of read more here.
Keywords: adiposity ascorbic; invited response; response new; local adiposity ... See more keywords
New Treatment Strategies for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0372-3
Abstract: Purpose of ReviewTo review recent studies that address important questions regarding the treatment of Philadelphia chromosome-positive ALL.Recent FindingsLess intensive non-myelosuppressive induction approaches can produce comparable anti-leukemic responses with less toxicity. Second-generation tyrosine kinase inhibitors (TKIs)… read more here.
Keywords: new treatment; treatment strategies; chromosome positive; philadelphia chromosome ... See more keywords
Collaboration for rare diabetes: understanding new treatment options for Wolfram syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02622-3
Abstract: Wolfram Syndrome is a very rare genetic disease causing diabetes mellitus, blindness, deafness, diabetes insipidus, and progressive brainstem degeneration. Neurologic symptoms of affected patients include ataxia, sleep apnea, loss of bladder control, dysphagia, loss of… read more here.
Keywords: collaboration rare; rare diabetes; wolfram syndrome; understanding new ... See more keywords
Orbitofrontal Cortex: A ‘Non-rewarding’ New Treatment Target in Depression?
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2018.11.057
Abstract: Self-perpetuating activity in lateral orbitofrontal regions has been theorized to sustain the negative thoughts and emotions of depression. A new study demonstrates that disrupting such activity may yield rapid improvements in mood state, pointing the… read more here.
Keywords: treatment; rewarding new; orbitofrontal cortex; cortex non ... See more keywords
Supralevator abscess: New treatment for an uncommon aetiology: Case report
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2019.05.016
Abstract: Highlights • Proper drainage of supralevantor abscess should be achieved for the fistulae path.• After supralevator abscess resolution the drain should be taken off and marsupialization with ENDO GIA® should be performed.• It is possible… read more here.
Keywords: abscess new; case; supralevator; new treatment ... See more keywords
Is ravulizumab the new treatment of choice for atypical hemolytic uremic syndrome (aHUS)?
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.03.011
Abstract: Ravulizumab, a new long-acting C5 inhibitor, recently received FDA approval for the treatment of aHUS. Rates of complete thrombotic microangiopathy response were similar to those observed in major eculizumab trials; however, fewer patients in the… read more here.
Keywords: treatment; treatment choice; choice atypical; ravulizumab new ... See more keywords
Coronary lithotripsy: a new treatment for severe calcified lesions
Sign Up to like & getrecommendations! Published in 2019 at "Acta Cardiologica"
DOI: 10.1080/00015385.2018.1558749
Abstract: A 72-year-old male was admitted for unstable angina due to severe in-stent restenosis (Figure 1). After several attempts using high pressure non compliant balloons, it was impossible to properly prepare the vessel as a result… read more here.
Keywords: figure; treatment; coronary lithotripsy; lithotripsy new ... See more keywords
New treatment directions for IPF: current status of ongoing and upcoming clinical trials
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2017.1335601
Abstract: ABSTRACT Introduction: The main objective of this review is to explore the wide and expanding field of new clinical trials in IPF. Recent trials have confirmed the efficacy of the approved drugs pirfenidone and nintedanib;… read more here.
Keywords: medicine; upcoming clinical; clinical trials; new treatment ... See more keywords
Calorie Restriction as a New Treatment of Inflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in nutrition"
DOI: 10.1093/advances/nmaa179
Abstract: Immoderate calorie intake coupled with a sedentary lifestyle are major determinants of health issues and inflammatory diseases in modern society. The balance between energy consumption and energy expenditure is critical for longevity. Excessive energy intake… read more here.
Keywords: inflammatory diseases; restriction new; new treatment; calorie restriction ... See more keywords
New drugs for multiple sclerosis: new treatment algorithms
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001063
Abstract: Purpose of review To discuss recent changes in the multiple sclerosis (MS) treatment algorithm and to present therapies currently in MS clinical trials. Recent findings High efficacy disease modifying therapies are optimally beneficial when used… read more here.
Keywords: new drugs; sclerosis new; new treatment; drugs multiple ... See more keywords