Mechanism of lncRNA H19 in Regulating Pulmonary Injury in Hyperoxia-Induced Bronchopulmonary Dysplasia Newborn Mice.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of perinatology"
DOI: 10.1055/s-0040-1721498
Abstract: OBJECTIVE  Bronchopulmonary dysplasia (BPD) is a pulmonary injury related to inflammation and is a major cause of premature infant death. Long noncoding RNAs (lncRNAs) are important regulators in pulmonary injury and inflammation. We investigated the… read more here.
Keywords: lncrna h19; newborn mice; pulmonary injury; mice ... See more keywords
Biodistribution of transplanted hematopoietic precursor cells injected through different administration routes in newborn mice.
Sign Up to like & getrecommendations! Published in 2021 at "Human gene therapy"
DOI: 10.1089/hum.2019.191
Abstract: Hematopoietic stem cell transplantation has been studied for several decades now, mostly as a treatment for malignancies and hematological diseases but also for genetic metabolic disorders. Since many diseases that could be potentially treated with… read more here.
Keywords: administration; biodistribution; biodistribution transplanted; transplanted hematopoietic ... See more keywords
Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection
Sign Up to like & getrecommendations! Published in 2017 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aaf9412
Abstract: Postnatal colonization by intestinal commensal bacteria directs migration of innate lymphoid cells to the lungs and promotes resistance of newborn mice to pneumonia. Gut microbiota: A driving force in lung mucosal defense Interactions between the… read more here.
Keywords: commensal bacteria; commensal; resistance; newborn mice ... See more keywords
Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Thrombosis and haemostasis"
DOI: 10.1160/th17-06-0433
Abstract: Congenital amegakaryocytic thrombocytopaenia (CAMT) is a disorder caused by c-MPL mutations that impair thrombopoietin (TPO) signalling, resulting in a near absence of megakaryocytes (MKs). While this phenotype is consistent in adults, neonates with CAMT can… read more here.
Keywords: developmental stage; stage specific; tpo; mice ... See more keywords
Effects of antioxidant MnTBAP on angiogenesis in newborn mice with hyperoxic lung injury.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neonatal-perinatal medicine"
DOI: 10.3233/npm-200483
Abstract: BACKGROUND Oxygen toxicity mediated by reactive oxygen species (ROS) plays an essential role in the development of bronchopulmonary dysplasia in premature infants. By reducing oxidative stress, antioxidants protect the immature lung. We studied the effects… read more here.
Keywords: expression; newborn mice; angiogenesis; histopathology ... See more keywords
Therapeutic potential of fetal liver cell transplantation in hemophilia A mice
Sign Up to like & getrecommendations! Published in 2023 at "Haematologica"
DOI: 10.3324/haematol.2022.282001
Abstract: Hemophilia A (HA) cell therapy approaches in pediatric individuals require suitable factor (F)VIII-producing cells for stable engraftment. Liver sinusoidal endothelial cells (LSEC) and hematopoietic stem cells (HSC) have been demonstrated to be suitable for the… read more here.
Keywords: fetal liver; newborn mice; liver; therapeutic potential ... See more keywords