Health Care Resource Utilization in Management of Opioid-Naive Patients With Newly Diagnosed Neck Pain
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DOI: 10.1001/jamanetworkopen.2022.22062
Abstract: Key Points Question What are common health care utilization patterns for management of newly diagnosed acute neck pain and how are they associated with care delivery? Findings In this cross-sectional study of 679 030 adults conducted… read more here.
Keywords: neck pain; utilization; newly diagnosed; care ... See more keywords
Adjuvant Temozolomide Chemotherapy With or Without Interferon Alfa Among Patients With Newly Diagnosed High-grade Gliomas: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.53285
Abstract: Importance High-grade gliomas (HGGs) constitute the most common and aggressive primary brain tumor, with 5-year survival rates of 30.9% for grade 3 gliomas and 6.6% for grade 4 gliomas. The add-on efficacy of interferon alfa… read more here.
Keywords: grade gliomas; patients newly; newly diagnosed; alfa ... See more keywords
Tolerability of Antiseizure Medications in Individuals With Newly Diagnosed Epilepsy.
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DOI: 10.1001/jamaneurol.2020.0032
Abstract: Importance Tolerability is a key determinant of the effectiveness of epilepsy treatment. It is important to evaluate whether the overall tolerability has improved. Objective To identify factors associated with poor tolerability of antiseizure medications (ASMs)… read more here.
Keywords: epilepsy; newly diagnosed; tolerability antiseizure; tolerability ... See more keywords
Prevalence of Prior Cancer Among Persons Newly Diagnosed With Cancer: An Initial Report From the Surveillance, Epidemiology, and End Results Program
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DOI: 10.1001/jamaoncol.2017.3605
Abstract: Importance The US cancer survivor population is rapidly growing. Cancer survivors are frequently excluded from cancer clinical trials and observational research. Objective To examine prevalence of prior cancer among individuals newly diagnosed with cancer. Design,… read more here.
Keywords: prevalence prior; newly diagnosed; epidemiology; diagnosed cancer ... See more keywords
Efficacy and Safety of a Pegasparaginase-Based Chemotherapy Regimen vs an L-asparaginase-Based Chemotherapy Regimen for Newly Diagnosed Advanced Extranodal Natural Killer/T-Cell Lymphoma: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.1968
Abstract: Importance The L-asparaginase-based SMILE (dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide) chemotherapy regimen has shown higher response rates and survival benefit over an anthracycline-containing regimen. However, the safety profile was not satisfied. A well-tolerated regimen with… read more here.
Keywords: smile group; ddgp group; chemotherapy regimen; newly diagnosed ... See more keywords
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study
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DOI: 10.1002/1878-0261.12790
Abstract: Glioblastoma (GBM) is an incurable brain tumor for which new treatment strategies are urgently needed. Next‐generation sequencing of GBM has most often been performed retrospectively and on archival tissue from both diagnostic and relapse surgeries… read more here.
Keywords: glioblastoma; newly diagnosed; treatment; study ... See more keywords
Peripheral blood biomarkers of early immune reconstitution in newly diagnosed multiple myeloma
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DOI: 10.1002/ajh.25365
Abstract: Peripheral blood biomarkers of tumor microenvironment and immune surveillance are independent prognostic factors in multiple myeloma. The timing and prognostic impact of immune reconstitution has been studied after autologous hematopoietic stem cell transplantation, less is… read more here.
Keywords: early immune; newly diagnosed; reconstitution; multiple myeloma ... See more keywords
Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow‐up from a phase 1b study
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DOI: 10.1002/ajh.26039
Abstract: This analysis represents the longest‐term follow‐up for patients with acute myeloid leukemia (AML) treated with 400 mg of venetoclax plus azacitidine or decitabine. Adults with newly diagnosed AML ineligible for intensive chemotherapy were enrolled in an… read more here.
Keywords: newly diagnosed; term follow; myeloid leukemia; venetoclax plus ... See more keywords
A phase 1b study of once‐weekly carfilzomib combined with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma
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DOI: 10.1002/ajh.26041
Abstract: Twice‐weekly carfilzomib with lenalidomide‐dexamethasone (Rd) is an effective regimen for newly diagnosed multiple myeloma (NDMM). Here we evaluated once‐weekly carfilzomib with Rd (once‐weekly KRd) in NDMM patients. The NDMM patients were enrolled regardless of transplant… read more here.
Keywords: newly diagnosed; multiple myeloma; weekly carfilzomib; carfilzomib ... See more keywords
Urgent cytoreduction for newly diagnosed acute myeloid leukemia patients allows acquisition of pretreatment genomic data and enrollment on investigational clinical trials
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26572
Abstract: Newly diagnosed acute myeloid leukemia is often deemed a medical emergency, requiring urgent treatment. This is in contradiction with the need for accurate cytogenetic and molecular data, which is not immediately available, to select optimal… read more here.
Keywords: cytoreduction; myeloid leukemia; newly diagnosed; group ... See more keywords
Changes in functional connectivity in newly diagnosed self‐limited epilepsy with centrotemporal spikes and cognitive impairment: An MEG study
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DOI: 10.1002/brb3.2830
Abstract: Our purpose was to explore the relationship between cognitive impairment and neural network changes in patients newly diagnosed with self‐limited epilepsy with centrotemporal spikes (SeLECTS). read more here.
Keywords: epilepsy centrotemporal; diagnosed self; limited epilepsy; newly diagnosed ... See more keywords