Understanding Titin Variants in the Age of Next-Generation Sequencing-A Titanic Challenge.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2017.3068
Abstract: The titin gene (TTN), with its 364 exons, encodes the largest human protein. It gives rise to a dizzying array of alternatively spliced isoforms differentially expressed in various skeletal muscles, heart, and in development. Titin… read more here.
Keywords: challenge; ttn; gene; next generation ... See more keywords
Next-Generation Alternative Payment Models in Oncology-Will Precision Preclude Participation?
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.7179
Abstract: This Viewpoint proposes 3 changes to the Enhancing Oncology Model of the US Centers for Medicare & Medicaid Services. read more here.
Keywords: oncology; models oncology; payment models; alternative payment ... See more keywords
Next‐generation disease modeling with direct conversion: a new path to old neurons
Sign Up to like & getrecommendations! Published in 2019 at "Febs Letters"
DOI: 10.1002/1873-3468.13678
Abstract: Within just over a decade, human reprogramming‐based disease modeling has developed from a rather outlandish idea into an essential part of disease research. While iPSCs are a valuable tool for modeling developmental and monogenetic disorders,… read more here.
Keywords: disease; direct conversion; generation disease; disease modeling ... See more keywords
Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13311
Abstract: IDH1 and IDH2 somatic mutations have been identified in solid tumors and blood malignancies. The development of inhibitors of mutant IDH1 and IDH2 in the past few years has prompted the development of a fast… read more here.
Keywords: multiplexed pcr; two new; detection; next generation ... See more keywords
The Technological Advancement to Engineer Next‐Generation Stent‐Grafts: Design, Material, and Fabrication Techniques
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200271
Abstract: Endovascular treatment of aortic disorders has gained wide acceptance due to reduced physiological burden to the patient compared to open surgery, and ongoing stent‐graft evolution has made aortic repair an option for patients with more… read more here.
Keywords: engineer next; next generation; advancement engineer; stent grafts ... See more keywords
Organic Bioelectronics: From Functional Materials to Next-Generation Devices and Power Sources.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202001439
Abstract: Conjugated polymers (CPs) possess a unique set of features setting them apart from other materials. These properties make them ideal when interfacing the biological world electronically. Their mixed electronic and ionic conductivity can be used… read more here.
Keywords: functional materials; next generation; materials next; power sources ... See more keywords
Large-area Uniform 1-nm-level Amorphous Carbon Layers from 3D Conformal Polymer Brushes. A "Next-generation" Cu Diffusion Barrier?
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202110454
Abstract: A reliable method for preparing a conformal amorphous carbon (a-C) layer with a thickness of 1-nm-level, was tested as a possible Cu diffusion barrier layer for next-generation ultrahigh density semiconductor device miniaturization. A polystyrene brush… read more here.
Keywords: next generation; amorphous carbon; diffusion; barrier ... See more keywords
Functional MXene‐Based Materials for Next‐Generation Rechargeable Batteries
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204988
Abstract: MXenes are seen as an exceptional candidate to reshape the future of energy with their viable surface chemistry, ultrathin 2D structure, and excellent electronic conductivity. The extensive research efforts bring about rapid expansion of the… read more here.
Keywords: next generation; based materials; mxene based; rechargeable batteries ... See more keywords
Liquid Crystals for Advanced Smart Devices with Microwave and Millimeter-Wave Applications: Recent Progress for Next-generation Communications.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202302474
Abstract: Liquid crystals (LCs) technology have a well-established history of applications in visible light, particularly in the display industry. However, with the rapid growth in communication technology, LCs have become a topic of current interest for… read more here.
Keywords: advanced smart; liquid crystals; microwave millimeter; millimeter wave ... See more keywords
Bipolar Electrodes for Next‐Generation Rechargeable Batteries
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202001207
Abstract: Abstract The development of advanced rechargeable batteries provides a great opportunity for basic and applied researchers to collectively overcome challenging scientific and technological barriers that directly address a critical need for energy storage. In addition… read more here.
Keywords: electrodes next; rechargeable batteries; bipolar electrodes; battery ... See more keywords
2D Materials Enabled Next‐Generation Integrated Optoelectronics: from Fabrication to Applications
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202003834
Abstract: Abstract 2D materials, such as graphene, black phosphorous and transition metal dichalcogenides, have gained persistent attention in the past few years thanks to their unique properties for optoelectronics. More importantly, introducing 2D materials into silicon… read more here.
Keywords: enabled next; fabrication; materials enabled; generation integrated ... See more keywords