Abstract 1642: Next trip: a promising CK1α-selective molecular glue degrader in MSS colorectal cancer
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DOI: 10.1158/1538-7445.am2025-1642
Abstract: Casein kinase 1α (CK1α) is a serine/threonine kinase that plays a critical role in cellular homeostasis. In previous studies, CK1α promotes p53 inactivation by regulating MDM2 and MDMX, and this mechanism may represent a promising… read more here.
Keywords: colorectal cancer; ck1 selective; cancer; next trip ... See more keywords