Neurofibromatosis type 1 (Nf1)‐mutant mice exhibit increased sleep fragmentation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Sleep Research"
DOI: 10.1111/jsr.12816
Abstract: Neurofibromatosis type 1 (NF1) is a neurodevelopmental disorder in which affected children and adults are at a higher risk of sleep disorders. In an effort to identify potential sleep disturbances in a small animal model,… read more here.
Keywords: type nf1; nf1 mutant; neurofibromatosis type; nf1cko mice ... See more keywords
Abstract 3414: The pan-RAF inhibitor tovorafenib suppresses NF1-mutant glioma through upregulation of FOXO1 and triggering of oncogene-induced senescence
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3414
Abstract: Pediatric low-grade glioma (pLGG) is the most common childhood brain tumor. Patients with pLGG often have significant lifelong disabilities due to the location of the tumor and tumor treatments, including surgery, chemotherapy, and radiation. The… read more here.
Keywords: mutant glioma; tovorafenib; senescence; foxo1 ... See more keywords