Induction of Short NFATc1/αA Isoform Interferes with Peripheral B Cell Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00032
Abstract: In lymphocytes, immune receptor signals induce the rapid nuclear translocation of preformed cytosolic NFAT proteins. Along with co-stimulatory signals, persistent immune receptor signals lead to high levels of NFATc1/αA, a short NFATc1 isoform, in effector… read more here.
Keywords: nfatc1; nfatc1 isoform; expression; short nfatc1 ... See more keywords
NFATc1/αA and Blimp-1 Support the Follicular and Effector Phenotype of Tregs
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.791100
Abstract: CD4+CXCR5+Foxp3+ T-follicular regulatory (TFR) cells control the germinal center responses. Like T-follicular helper cells, they express high levels of Nuclear Factor of Activated T-cells c1 , predominantly its short isoform NFATc1/αA. Ablation of NFATc1 in… read more here.
Keywords: cxcr5; effector; tfr; tregs ... See more keywords
Osteoclast Differentiation is Downregulated by Select Polyphenolic Fractions from Dried Plum via Suppression of MAPKs and Nfatc1 in Mouse C57BL/6 Primary Bone Marrow Cells
Sign Up to like & getrecommendations! Published in 2017 at "Current Developments in Nutrition"
DOI: 10.3945/cdn.117.000406
Abstract: Abstract Background: Clinical and preclinical studies have shown that dietary supplementation with dried plum improves bone health. These osteoprotective effects are a result, in part, of the antiresorptive properties of the fruit, which appear to… read more here.
Keywords: osteoclast differentiation; nfatc1; primary bone; dried plum ... See more keywords