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∆nFGF1 Protects β-Cells against High Glucose-Induced Apoptosis via the AMPK/SIRT1/PGC-1α Axis

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1 Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1231970

Abstract: Long-term exposure to high glucose leads to β-cell dysfunction and death. Fibroblast growth factor 1 (FGF1) has emerged as a promising diabetes treatment, but its pharmaceutical role and mechanism against glucolipotoxicity-induced β-cell dysfunction remain uncharacterized.… read more here.

Keywords: nfgf1 protects; sirt1 pgc; apoptosis; ampk sirt1 ... See more keywords