NFkB‐signaling promotes glial reactivity and suppresses Müller glia‐mediated neuron regeneration in the mammalian retina
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DOI: 10.1002/glia.24181
Abstract: Müller glia (MG) in mammalian retinas are incapable of regenerating neurons after damage, whereas the MG in lower vertebrates regenerate functional neurons. Identification of cell signaling pathways and gene regulatory networks that regulate MG‐mediated regeneration… read more here.
Keywords: regeneration; ller glia; glia; damage ... See more keywords
Abstract 7545: Epigenetic plasticity in rewiring DNMT1/UHRF1-RB1- NFkB signaling circuit regulates asbestos-induced mesothelial malignant transformation
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DOI: 10.1158/1538-7445.am2024-7545
Abstract: The exact mechanisms underlying the causal relationship between asbestos exposure and malignant mesothelioma (MM) have yet to be elucidated. Widespread genomic and epigenomic alterations are being implicated in rewiring of oncogenic signaling networks which may… read more here.
Keywords: nfkb signaling; dnmt1 uhrf1; rb1 nfkb; signaling circuit ... See more keywords