NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-85335-x
Abstract: The present work addressed the hypothesis that NG2/CSPG4, CD146/MCAM, and VAP1/AOC3 are target genes of myocardin-related transcription factors (MRTFs: myocardin/MYOCD, MRTF-A/MKL1, MRTF-B/MKL2) and serum response factor (SRF). Using a bioinformatics approach, we found that CSPG4,… read more here.
Keywords: aoc3; mcam aoc3; cd146 mcam; mcam ... See more keywords
MMP-13 Regulates Matrix Binding and Internalization of NG2/CSGP4 in Mandibular Fibrochondrocytes
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731478
Abstract: Objective: Post-traumatic osteoarthritis (OA) is associated with cartilage degradation resulting in changes in cell-matrix mediated signaling after injury. Matrix metalloproteinase-13 (MMP13) is a critical enzyme in this process, degrading the extracellular matrix and modifying receptors.… read more here.
Keywords: matrix binding; mandibular fibrochondrocytes; ng2 cspg4; internalization ... See more keywords
Myelin Debris Stimulates NG2/CSPG4 Expression in Bone Marrow-Derived Macrophages in the Injured Spinal Cord
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.651827
Abstract: Although the increased expression of members of the chondroitin sulfate proteoglycan family, such as neuron-glial antigen 2 (NG2), have been well documented after an injury to the spinal cord, a complete picture as to the… read more here.
Keywords: cspg4 expression; spinal cord; expression; ng2 cspg4 ... See more keywords
The Significance of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Human Gliomas
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DOI: 10.3390/ijms19092724
Abstract: Neuron glial antigen 2 (NG2) is a chondroitin sulphate proteoglycan 4 (CSPG4) that occurs in developing and adult central nervous systems (CNSs) as a marker of oligodendrocyte precursor cells (OPCs) together with platelet-derived growth factor… read more here.
Keywords: chondroitin; cspg4; proteoglycan cspg4; human gliomas ... See more keywords