Topical treatments of Saussurea costus root and Thuja orientalis L. synergistically alleviate atopic dermatitis-like skin lesions by inhibiting protease-activated receptor-2 and NF-κB signaling in HaCaT cells and Nc/Nga mice.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.01.055
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The root of Saussurea costus (Aucklandia lappa Decne, Aucklandiae Radix, SC) and Thuja orientalis L. (TOL) have been traditionally used as anti-inflammatory agents in Korea. However, they have not been studied for the… read more here.
Keywords: hacat cells; tol; nga mice; dorsal skin ... See more keywords
Immediate‐type allergic and protease‐mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13322
Abstract: Atopic dermatitis (AD)‐like dermatitis can be induced by repeated topical application of an ointment containing Dermatophagoides farinae body (Dfb) extract in NC/Nga mice. This AD‐like murine model also exhibits a biphasic increase in the number… read more here.
Keywords: topical application; dermatophagoides farinae; application; nga mice ... See more keywords
The Role of Proteasome Inhibitor MG132 in 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis in NC/Nga Mice
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DOI: 10.1159/000488155
Abstract: Background: Although immunosuppressants for therapy of atopic dermatitis (AD) are still being sought, proteasome inhibitors are also potential candidates for the treatment of AD. Proteasome inhibitors exert various effects by blocking proteasomal degradation and help… read more here.
Keywords: proteasome inhibitor; mg132 administration; atopic dermatitis; nga mice ... See more keywords
Effect of administrating polysaccharide from black currant (Ribes nigrum L.) on atopic dermatitis in NC/Nga mice
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience of Microbiota, Food and Health"
DOI: 10.12938/bmfh.17-014
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease that causes dry skin and functional disruption of the skin barrier. AD is often accompanied by allergic inflammation. AD patient suffer from heavy itching, and their… read more here.
Keywords: atopic dermatitis; administration; effect; nga mice ... See more keywords
Sargassum horneri extract containing polyphenol alleviates DNCB-induced atopic dermatitis in NC/Nga mice through restoring skin barrier function.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-473
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by skin barrier dysfunction. Sargassum horneri is a brown alga that has been widely used in traditional medicine of eastern Asian countries. Recent studies proved… read more here.
Keywords: nga mice; skin barrier; function; dncb induced ... See more keywords
Inhibitory Effects of Donkey Hide Gelatin on DNCB-Induced Atopic Dermatitis in NC/Nga Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.896450
Abstract: The increase of atopic dermatitis has led to higher socio-economic cost and raised a need for alternative medicine as novel therapeutic agents. In this study, we aimed to evaluate the inhibitory effects of Donkey Hide… read more here.
Keywords: inhibitory effects; nga mice; atopic dermatitis; dermatitis ... See more keywords
Dimerized Translationally Controlled Tumor Protein-Binding Peptide Ameliorates Atopic Dermatitis in NC/Nga Mice
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DOI: 10.3390/ijms18020256
Abstract: Our previous study showed that dimerized translationally controlled tumor protein (dTCTP) plays a role in the pathogenesis of allergic diseases, such as asthma and allergic rhinitis. A 7-mer peptide, called dTCTP-binding peptide 2 (dTBP2), binds… read more here.
Keywords: controlled tumor; translationally controlled; dtbp2; tumor protein ... See more keywords
Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression
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DOI: 10.3390/md19110622
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease in which skin barrier dysfunction leads to dryness, pruritus, and erythematous lesions. AD is triggered by immune imbalance and oxidative stress. Echinochrome A (Ech A), a… read more here.
Keywords: skin lesions; lesions nga; treatment; atopic dermatitis ... See more keywords
Galectin-9 Induced by Dietary Prebiotics Regulates Immunomodulation to Reduce Atopic Dermatitis Symptoms in 1-Chloro-2,4-Dinitrobenzene (DNCB)-Treated NC/Nga Mice.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.2005.05017
Abstract: Atopic dermatitis (AD) is a skin disorder that causes chronic itch. We investigated the inhibitory effects of a mixture of prebiotic short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (scGOS/lcFOS), inulin, or β-glucan on AD development in 1-chloro-2,4-dinitrobenzene… read more here.
Keywords: treated nga; dncb treated; atopic dermatitis; mice ... See more keywords