The novel synthetic microneurotrophin BNN27 protects mature oligodendrocytes against cuprizone‐induced death, through the NGF receptor TrkA
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23170
Abstract: BNN27, a member of a chemical library of C17‐spiroepoxy derivatives of the neurosteroid DHEA, has been shown to regulate neuronal survival through its selective interaction with NGF receptors (TrkA and p75NTR), but its role on… read more here.
Keywords: cuprizone; novel synthetic; mature oligodendrocytes; ngf ... See more keywords
NGF protects bone marrow mesenchymal stem cells against 2,5-hexanedione-induced apoptosis in vitro via Akt/Bad signal pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03518-7
Abstract: Mesenchymal stem cell transplantation has been proposed as a promising therapy for regeneration of damaged tissues—especially, bone marrow mesenchymal stem cell (BMSC) transplantation therapy is considered to be an effective strategy for treating various injures… read more here.
Keywords: apoptosis; ngf; bmscs; akt bad ... See more keywords
Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15130
Abstract: Pancreatic cancer is one of the deadliest human cancers, whose progression is highly dependent on the nervous microenvironment. The suppression of gene expression of nerve growth factor (NGF) may have great potential in pancreatic cancer… read more here.
Keywords: treatment; pancreatic cancer; ngf; cancer ... See more keywords
Nerve Growth Factor in Psychiatric Disorders: A Scoping Review
Sign Up to like & getrecommendations! Published in 2023 at "Indian Journal of Psychological Medicine"
DOI: 10.1177/02537176231162518
Abstract: Neurotrophins have been implicated in multiple psychiatric disorders. Nerve Growth Factor (NGF) is one of the major neurotrophins that has attracted much research interest. Therefore, we undertook, to the best of our knowledge, the first… read more here.
Keywords: psychiatric disorders; review; depression; nerve growth ... See more keywords
Nerve growth factor promotes the proliferation of Müller cells co-cultured with internal limiting membrane by regulating cell cycle via Trk-A/PI3K/Akt pathway
Sign Up to like & getrecommendations! Published in 2019 at "BMC Ophthalmology"
DOI: 10.1186/s12886-019-1142-x
Abstract: BackgroundNerve growth factor (NGF), produced by Müller cells, and internal limiting membrane (ILM) have fundamental roles in the development of full-thickness macular hole (FTMH). However, the potential crosstalk between NGF and ILM in FTMH is… read more here.
Keywords: ller; cell cycle; ilm; ngf ... See more keywords
Is seminal NGF-induced LH release in camelids mediated at the hypothalamus?
Sign Up to like & getrecommendations! Published in 2023 at "Reproduction"
DOI: 10.1530/rep-22-0331
Abstract: Ovulation in camelids is triggered by seminal nerve growth factor (NGF). The mechanism of action of NGF appears to occur via the central nervous system. In this study, we tested the hypothesis that NGF acts… read more here.
Keywords: administration; ngf induced; experiment; release ... See more keywords
Improved Production of Recombinant Human β-NGF in Escherichia coli – a Bioreactor Scale Study
Sign Up to like & getrecommendations! Published in 2018 at "Polish Journal of Microbiology"
DOI: 10.21307/pjm-2018-045
Abstract: Abstract Human nerve growth factor β (β-NGF) is considered a major therapeutic agent for treatment of neurodegenerative diseases. We have previously reported the optimized conditions for β-NGF overproduction in Escherichia coli in a shake-flask culture.… read more here.
Keywords: post induction; production; escherichia coli; study ... See more keywords