The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease
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DOI: 10.1038/s41380-020-0797-2
Abstract: The NGF metabolic pathway entails the proteins that mature pro-nerve growth factor (proNGF) to NGF and those that degrade NGF. Basal forebrain cholinergic neurons require NGF for maintenance of cholinergic phenotype, are critical for cognition,… read more here.
Keywords: metabolic pathway; prongf; pathology; ngf metabolic ... See more keywords