Electroacupuncture improves neurogenic bladder dysfunction through activation of NGF/TrkA signaling in a rat model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28272
Abstract: To observe the effect of electroacupuncture on the morphological change of the bladder tissue and the protein expression levels of NGF, TrkA, p‐TrkA, AKT, and p‐AKT in the bladder tissue of rats with neurogenic bladder… read more here.
Keywords: neurogenic bladder; ngf trka; bladder; electroacupuncture improves ... See more keywords
Whole-tissue 3D imaging reveals intra-adipose sympathetic plasticity regulated by NGF-TrkA signal in cold-induced beiging
Sign Up to like & getrecommendations! Published in 2018 at "Protein & Cell"
DOI: 10.1007/s13238-018-0528-5
Abstract: Sympathetic arborizations act as the essential efferent signals in regulating the metabolism of peripheral organs including white adipose tissues (WAT). However, whether these local neural structures would be of plastic nature, and how such plasticity… read more here.
Keywords: cold induced; ngf trka; sympathetic plasticity; adipose sympathetic ... See more keywords
PERINEURAL INVASION IN ORAL SQUAMOUS CELL CARCINOMA: INCIDENCE, CLINICAL IMPACT AND MOLECULAR INSIGHT
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.03.032
Abstract: Background Perineural invasion (PNI) has been associated with poor prognosis in oral squamous cell carcinoma (OSCC). Nerve growth factor (NGF) and its receptor tyrosine kinase A (TrkA) may play a role in PNI in OSCC.… read more here.
Keywords: ngf trka; oral squamous; pathology; squamous cell ... See more keywords
Optical Activation of TrkA Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.8b00126
Abstract: Nerve growth factor/tropomyosin receptor kinase A (NGF/TrkA) signaling plays a key role in neuronal development, function, survival, and growth. The pathway is implicated in neurodegenerative disorders including Alzheimer's disease, chronic pain, inflammation, and cancer. NGF… read more here.
Keywords: ngf trka; trka; activation trka; trka signaling ... See more keywords
ARMS/Kidins220 regulates nociception by controlling BDNF secretion.
Sign Up to like & getrecommendations! Published in 2022 at "Pain"
DOI: 10.1097/j.pain.0000000000002741
Abstract: ABSTRACT Pain is an alarm mechanism to prevent body damage in response to noxious stimuli. The NGF/TrkA axis plays an essential role as pain mediator and several clinical trials using antibodies against NGF have been… read more here.
Keywords: arms kidins220; nociception; pain; ngf trka ... See more keywords
Upregulation of TRPV1 in spinal dorsal root ganglion by activating NGF‐TrkA pathway contributes to pelvic organ cross‐sensitisation in rats with experimental autoimmune prostatitis
Sign Up to like & getrecommendations! Published in 2019 at "Andrologia"
DOI: 10.1111/and.13302
Abstract: Chronic prostatitis/chronic pelvic pain syndrome (CP⁄CPPS) is the prostate gland inflammation characterised as genitourinary pain in the pelvic region. The rat experimental autoimmune prostatitis (EAP) was achieved to mimic CP⁄CPPS. The expressions of transient receptor… read more here.
Keywords: drg; ngf trka; group; autoimmune prostatitis ... See more keywords
The β-NGF/TrkA Signalling Pathway Is Associated With the Production of Anti-Nucleoprotein IgG in Convalescent COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.813300
Abstract: Background The presentation of SARS-CoV-2 infection varies from asymptomatic to severe COVID-19. Similarly, high variability in the presence, titre and duration of specific antibodies has been reported. While some host factors determining these differences, such… read more here.
Keywords: trka signalling; production; anti; ngf trka ... See more keywords
New Insights Into the Role of β-NGF/TrKA System in the Endometrium of Alpacas During Early Pregnancy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.583369
Abstract: One striking reproductive feature in South American camelids is that more than 90% of gestations are established in the left uterine horn (LUH). This phenomenon could be related to a differential vascular irrigation of the… read more here.
Keywords: pregnancy; ngf trka; endometrium; luh ... See more keywords
NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21207657
Abstract: Nerve Growth Factor (NGF) and its high-affinity receptor tropomyosin receptor kinase A (TRKA) increase their expression during the progression of epithelial ovarian cancer (EOC), promoting cell proliferation and angiogenesis through several oncogenic proteins, such as… read more here.
Keywords: epithelial ovarian; mir 145; 145 levels; ngf trka ... See more keywords
NGF/TRKA Promotes ADAM17-Dependent Cleavage of P75 in Ovarian Cells: Elucidating a Pro-Tumoral Mechanism
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042124
Abstract: Nerve growth factor (NGF) and its high-affinity receptor TRKA are overexpressed in epithelial ovarian cancer (EOC) displaying a crucial role in the disease progression. Otherwise, NGF interacts with its low-affinity receptor P75, activating pro-apoptotic pathways.… read more here.
Keywords: cleavage p75; p75 ovarian; trka; p75 ... See more keywords