Newly diagnosed isolated myeloid sarcoma–paired NGS panel analysis of extramedullary tumor and bone marrow
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04313-x
Abstract: Isolated myeloid sarcoma (MS) is a rare malignancy in which myeloid blast forms tumors at various locations while the bone marrow (BM) remains cytomorphologically free from disease. We analyzed isolated MS from four patients and… read more here.
Keywords: myeloid sarcoma; ngs panel; isolated myeloid; bone marrow ... See more keywords
Molecular subtype diagnosis of endometrial carcinoma: comparison of NGS panel and ProMisE classifier.
Sign Up to like & getrecommendations! Published in 2021 at "Human pathology"
DOI: 10.1016/j.humpath.2021.02.006
Abstract: OBJECTIVES The Cancer Genome Atlas-based molecular classification of endometrial carcinoma (EC) has the potential to better identify those patients whose disease is likely to behave differently than predicted when using traditional risk stratification, however, the… read more here.
Keywords: molecular subtype; ngs panel; subtype diagnosis;
PATH-50. ROUTINE MOLECULAR DIAGNOSIS OF GLIOMA PATIENTS USING A GLIOMA-SPECIFIC NGS PANEL
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.646
Abstract: The 2016 WHO classification requires molecular diagnosis in routine glioma diagnostics. However, analysis of key driver gene mutations and chromosome 1p/19q co-deletions cannot be performed in a single platform. In this study, we evaluated the… read more here.
Keywords: glioma patients; glioma; glioma specific; specific ngs ... See more keywords
NGS panel enhance precise diagnosis of myeloid neoplasms under WHO-HAEM5 and International Consensus Classification: An observational study
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000038556
Abstract: This study aimed to assess hematological diseases next-generation sequencing (NGS) panel enhances the diagnosis and classification of myeloid neoplasms (MN) using the 5th edition of the WHO Classification of Hematolymphoid Tumors (WHO-HAEM5) and the International… read more here.
Keywords: classification; diagnosis; myeloid neoplasms; ngs panel ... See more keywords
Moving towards a local testing solution for undetermined thyroid fine-needle aspirates: validation of a novel custom DNA-based NGS panel
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2021-207429
Abstract: Aims In thyroid cytopathology, the undetermined diagnostic categories still pose diagnostic challenges. Although next-generation sequencing (NGS) is a promising technique for the molecular testing of thyroid fine-needle aspiration (FNA) specimens, access to such technology can… read more here.
Keywords: thyroid fine; novel custom; fine needle; ngs panel ... See more keywords
Abstract 1035: Identification of fibroblast growth factor receptors (FGFRs) alterations (alts) at DNA and RNA-level by one-step next-generation sequencing (NGS) panel
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-1035
Abstract: Background: FGFR inhibitors are currently in clinical development or approved for urothelial cancer and cholangiocarcinoma with FGFR fusion (FUS) or/and mutation (MUT). AmoyDx FGFR 1-4 NGS Panel (FGFR-P) was developed for FGFR alts detection based… read more here.
Keywords: dna rna; cancer; fgfr; ngs panel ... See more keywords
Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0875-0
Abstract: Liquid biopsy by genotyping circulating tumor DNA (ctDNA) has provided a non-invasive approach in assessing tumor genomic alterations in clinical oncology. However, emerging evidence in clinical settings has shown significant discordance in the genomic alterations… read more here.
Keywords: tumor tissue; parallel ngs; ngs panel; panel testing ... See more keywords
Tumor mutation burden derived from large NGS panel as biomarker for immunotherapy response.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e23077
Abstract: e23077Background: Tumor mutation burden (TMB) is an informative biomarker for predicting response to immunotherapy in a growing number of malignancies. The TMB clinical applicability is limited due to cost and bioinformatics requirements of sequencing and… read more here.
Keywords: tumor mutation; ngs panel; large ngs; mutation burden ... See more keywords
Analytical validation of a 47-gene NGS panel for molecular profiling of myeloid neoplasms.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e18526
Abstract: e18526 Background: Molecular profiling can help diagnose, classify, and guide treatment of myeloid neoplasms. Next generation sequencing (NGS) is a powerful platform that can facilitate identification of actionable genetic alterations in multiple genes simultaneously. To… read more here.
Keywords: panel; myeloid neoplasms; ngs panel; coverage ... See more keywords
Performance of the AmpliSeq NGS panel in thyroid nodules with indeterminate cytology
Sign Up to like & getrecommendations! Published in 2024 at "European Thyroid Journal"
DOI: 10.1530/etj-24-0160
Abstract: Objective Fine-needle aspiration (FNA) cytological analysis fails to confirm the benignity or malignancy of Bethesda III, IV and V thyroid nodules. Molecular tests performed on FNA samples have demonstrated interesting results in improving the diagnosis… read more here.
Keywords: cytology; thyroid nodules; bethesda iii; ngs panel ... See more keywords
A multiplex targeted NGS panel for identifying pathogens in canine neurological and reproductive diseases
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2025.1591145
Abstract: Introduction Multiple pathogens can infect the canine reproductive and central nervous systems, including organisms that are zoonotic, such as Brucella canis, pathogenic Leptospira spp., Anaplasma phagocytophilum, Histoplasma capsulatum, and Blastomyces dermatitidis. In this study, we… read more here.
Keywords: panel; pcr assays; neurological reproductive; ngs panel ... See more keywords