New PEPPSI‐Pd‐NHC complexes bearing 4‐hydroxyphenylethyl group: Synthesis, characterization, molecular docking, and bioactivity properties
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200276
Abstract: Five 4‐hydroxyphenylethyl substituted pyridine enhanced, precatalyst, preparation, stabilization, and initiation‐Pd‐N‐heterocyclic carbene (PEPPSI‐Pd‐NHC) complexes are synthesized in a straightforward way. All PEPPSI‐Pd‐NHC complexes were prepared by mixing 4‐hydroxyphenylethyl substituted NHC precursors, palladium chloride, potassium carbonate, and… read more here.
Keywords: nhc complexes; bearing hydroxyphenylethyl; complexes bearing; new peppsi ... See more keywords
Metal NHC Complexes with Naphthalimide Ligands as DNA‐Interacting Antiproliferative Agents
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DOI: 10.1002/cmdc.201600557
Abstract: Naphthalimide‐based N‐heterocyclic carbene (NHC) complexes of the type [(1,5‐cyclooctadiene)(NHC)RhCl)] (4 a–c), [(p‐cymene)(NHC)RuCl2)] (5 a–c), and [(NHC)CuBr] (6 a–c) were synthesized and investigated as antiproliferative agents that target DNA. The cytotoxic effects were largely driven by the naphthalimide structure,… read more here.
Keywords: metal nhc; complexes naphthalimide; antiproliferative agents; ligands dna ... See more keywords
Well-Defined NHC-Ni Complexes as Catalysts: Preparation, Structures and Mechanistic Studies in Cross-Coupling Reactions.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical record"
DOI: 10.1002/tcr.202100204
Abstract: Developmental studies are ongoing to discover a way to utilise new N-heterocyclic carbene (NHC)-Ni complexes as catalysts. Using a bulky NHC ligand, it is possible to synthesise an NHC/phosphine-mixed heteroleptic Ni(II) complex, which can serve… read more here.
Keywords: complexes catalysts; well defined; reaction; nhc complexes ... See more keywords
Chemistry, structure, and biological roles of Au-NHC complexes as TrxR inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103552
Abstract: In recent years, the preparation of metal complexes and the introduction of biologically active organometalic compounds are new strategies in drug development. For this purpose, generally N-heterocyclic pharmaceutical agents have been used as promising nuclei.… read more here.
Keywords: complexes trxr; chemistry structure; trxr inhibition; chemistry ... See more keywords
New 4-vinylbenzyl-substituted bis(NHC)-Pd(II) complexes: Synthesis, characterization and the catalytic activity in the direct arylation reaction
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.12.019
Abstract: Abstract This study contains the synthesis of the new 4-vinylbenzyl substituted bis(NHC)-Pd(II) complexes and their catalytic activity in direct arylation reaction. The bis(NHC)-Pd(II) complexes have been prepared from Ag(I)NHC complexes by transmetallation method. The complexes… read more here.
Keywords: direct arylation; bis nhc; arylation reaction; nhc complexes ... See more keywords
Novel Silver-NHC complexes: Synthesis and anticancer properties
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2019.04.018
Abstract: Abstract The aim of this study was to present the synthesis, characterization and anticancer activities of two novel benzimidazole-based NHC salts (1a-b) and their silver(I) complexes (2a-b) with methylbenzyl and isopropylbenzyl chains. All compounds were… read more here.
Keywords: anticancer activities; synthesis; nhc complexes; cancer cells ... See more keywords
Synthesis, structure and characterization of picolyl and benzyl linked biphenyl nickel NHC complexes and their catalytic activity in Suzuki-Miyaura cross-coupling reactions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2021.121754
Abstract: Abstract Picolyl and benzyl linked biphenyl nickel NHC complexes [NiL1Br2] (1), [NiL2]Br2 (2) [NiL3]Br2 (3) and [NiL3(N3)2] (4) were synthesized and characterized by CHN, ESI-MS, 1H, 13C NMR and single crystal XRD. All complexes adopted… read more here.
Keywords: biphenyl nickel; benzyl linked; nhc complexes; nickel nhc ... See more keywords
CpNiBr(NHC) complexes as pre-catalysts in the chemoselective anaerobic oxidation of secondary aryl alcohols: Experimental and DFT studies
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Catalysis"
DOI: 10.1016/j.mcat.2016.12.023
Abstract: Abstract Nine Ni(II)-NHC complexes of the type [CpNiBr(NHC)], each containing either a symmetric or asymmetric alkyl/benzyl/phenylethyl imidazolium ligand, effectively catalysed the anaerobic oxidation of a series of secondary alcohols, including 1-phenylethanol to yield acetophenone. Catalytic… read more here.
Keywords: secondary alcohols; nhc complexes; anaerobic oxidation; cpnibr nhc ... See more keywords
Dinuclear silver(I)- and gold(I)-N-heterocyclic carbene complexes of N-alkyl substituted bis-benzimidazol-2-ylidenes with aliphatic spacer: Synthesis, characterizations and antibacterial studies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131187
Abstract: Abstract New series of dinuclear Ag(I)-NHC and Au(I)-NHC complexes (NHC = N-heterocyclic carbene) bearing n-alkyl homologous series with propylene spacers were synthesized. Initially, bis-benzimidazolium salts, 1-5 were synthesized via two steps n-alkylation reaction. The salts were then… read more here.
Keywords: antibacterial studies; nhc complexes; coli aureus; heterocyclic carbene ... See more keywords
PEPPSI type Pd(II)NHC complexes bearing chloro-/fluorobenzyl group: Synthesis, characterization, crystal structures, α-glycosidase and acetylcholinesterase inhibitory properties
Sign Up to like & getrecommendations! Published in 2021 at "Polyhedron"
DOI: 10.1016/j.poly.2021.115060
Abstract: Abstract This work reported the synthesis of a new PEPPSI (Pyridine Enhanced Precatalyst Preparation, Stabilization and Initiation) type Pd(II)N-heterocyclic carbene (NHC) complexes bearing halo-benzyl (4-florobenzyl and 2-chloro-4-florobenzyl) group. These new complexes were synthesized from the… read more here.
Keywords: nhc complexes; complexes bearing; crystal structures; peppsi type ... See more keywords
Late Lanthanide Macrocyclic Tetra-NHC Complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c03416
Abstract: An isostructural set of macrocyclic tetra-N-heterocyclic carbene (NHC) complexes were synthesized on late lanthanides including Lu, Yb, Ho, Dy, and Gd. They were characterized by single-crystal X-ray diffraction, multinuclear NMR, electrochemistry, and SQUID magnetometry. Solid-state… read more here.
Keywords: lanthanide macrocyclic; late lanthanide; macrocyclic tetra; nhc complexes ... See more keywords