PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
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DOI: 10.1126/sciadv.adg2834
Abstract: Nonhomologous end joining is a critical mechanism that repairs DNA double-strand breaks in human cells. In this work, we address the structural and functional role of the accessory protein PAXX [paralog of x-ray repair cross-complementing… read more here.
Keywords: paxx binding; binding nhej; nhej machinery; xlf ... See more keywords