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   Articles with "nhej mediated" as a keyword



APOL2 Stabilizes Ku80 to Confer NHEJ‐Mediated Radioresistance in Gastric Cancer

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202506294

Abstract: Radiotherapy is one of the most important adjuvant treatment methods for gastric cancer (GC). However, radioresistance remains a major clinical obstacle. In this study, APOL2 is identified as a key player in promoting non‐homologous end… read more here.

Keywords: gastric cancer; nhej mediated; radioresistance; apol2 ... See more keywords

TBX20 inhibits colorectal cancer tumorigenesis by impairing NHEJ-mediated DNA repair.

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recommendations! Published in 2022 at "Cancer science"

DOI: 10.1111/cas.15348

Abstract: DNA high methylation is one of driving force for colorectal carcinoma (CRC) pathogenesis. Transcription factors (TFs) can determine cell fate and play fundamental roles in multistep process of tumorigenesis. Dysregulation of DNA methylation of TFs… read more here.

Keywords: dna; dna repair; nhej mediated; crc ... See more keywords

T‐circle vector strategy increases NHEJ‐mediated site‐specific integration in soybean

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recommendations! Published in 2024 at "Plant Biotechnology Journal"

DOI: 10.1111/pbi.14311

Abstract: The soybean transgenic plant #83 is a two-copy transgenic event: one copy SSI at the chromosome 6 DT5.1 site (see S4 ), the other integrated at soybean phospholipase A1-I beta2 mRNA 5’ leader sequence (LOC100819591,… read more here.

Keywords: circle vector; strategy increases; increases nhej; site ... See more keywords

Abstract 3218: Maternal embryonic leucine zipper kinase (MELK) confers radioresistance in triple-negative breast cancers (TNBC) through a nonhomologous end joining (NHEJ)-mediated pathway

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recommendations! Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-3218

Abstract: Background: Increased rates of locoregional recurrence have been observed in TNBC despite the use of radiation (RT); therefore, approaches that result in radiosensitizaton in TNBC may improve clinical outcomes. Despite some controversy as to the… read more here.

Keywords: nhej mediated; melk; kinase; melk confers ... See more keywords