Articles with "nicastrin" as a keyword



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Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot

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Published in 2019 at "F1000Research"

DOI: 10.12688/f1000research.19803.2

Abstract: Nicastrin (NCSTN) is a transmembrane glycoprotein that is part of the gamma-secretase complex. Gamma-secretase is a protease complex that cleaves type-I single-pass transmembrane proteins. There are many potential substrates for this complex, including NOTCH receptors… read more here.

Keywords: nicastrin; detect endogenous; antibody; antibody detect ... See more keywords