Activation of Notch1 signaling by HTLV-1 Tax promotes proliferation of adult T-cell leukemia cells.
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DOI: 10.1016/j.bbrc.2019.03.094
Abstract: Human T-cell leukemia virus 1 (HTLV-1), an oncogenic retrovirus, and Notch1 signaling, implicated in tumor formation and progression, are both associated with the development of adult T-cell leukemia (ATL). Here we explored the possibility of… read more here.
Keywords: tax; cell leukemia; notch1 signaling; nicd ... See more keywords