Nickel-catalysed C O bond reduction of 2,4,6-triaryloxy-1,3,5-triazines in 2-methyltetrahydrofuran
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2018.09.009
Abstract: Abstract A nickel-catalysed reduction of phenol derivatives activated by 2,4,6-trichloro-1,3,5-triazine (TCT) in ecofriendly 2-methyltetrahydrofuran (2-MeTHF) is described. The phenol-TCT derivatives were readily prepared using grinding method in short time without further purification. This catalytic system… read more here.
Keywords: bond reduction; reduction; nickel catalysed; phenol tct ... See more keywords
Base-Free Nickel-Catalysed DecarbonylativeSuzuki-Miyaura Coupling of Acid Fluorides
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DOI: 10.1038/s41586-018-0628-7
Abstract: The Suzuki–Miyaura cross-coupling of organoboron nucleophiles with aryl halide electrophiles is one of the most widely used carbon–carbon bond-forming reactions in organic and medicinal chemistry1,2. A key challenge associated with these transformations is that they… read more here.
Keywords: boronic acids; miyaura coupling; nickel catalysed; base ... See more keywords
Nickel-catalysed carbonylative homologation of aryl iodides
Sign Up to like & getrecommendations! Published in 2018 at "Communications Chemistry"
DOI: 10.1038/s42004-018-0091-2
Abstract: Homologation is an important organic transformation which extends the carbon chain of a parent molecule, and many procedures have been established. However, although carbonylation reactions are now well developed as valuable methods for the synthesis… read more here.
Keywords: carbonylative homologation; nickel catalysed; aryl iodides; homologation ... See more keywords
Nickel-catalysed direct C2-arylation of N-heterocyclic carbenes.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt03099a
Abstract: A highly efficient nickel catalysed method for the direct C2-arylation of N-heterocyclic carbenes (NHCs) is reported. This protocol enables a facile access to C2-arylated imidazolium salts (NHC-Ar)X (X = Cl, Br, I or OTf). Experimental… read more here.
Keywords: direct arylation; nickel catalysed; heterocyclic carbenes; arylation heterocyclic ... See more keywords
Nickel-catalysed alkylation of C(sp3)-H bonds with alcohols: direct access to functionalised N-heteroaromatics.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc06370b
Abstract: The first base-metal catalysed coupling of primary alcohols with methyl-N-heteroaromatics is reported. The use of an earth abundant and nonprecious NiBr2/L1 system enables access to a series of C(sp3)-alkylated N-heteroaromatics. Mechanistic studies have established the… read more here.
Keywords: catalysed alkylation; sp3; nickel catalysed; alkylation sp3 ... See more keywords
Nickel-catalysed direct α-olefination of alkyl substituted N-heteroarenes with alcohols.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc03591e
Abstract: Catalytic α-olefination of alkylheteroarenes with primary alcohols via dehydrogenative coupling is presented. A simple nickel catalyst system stabilised by readily available nitrogen ligands enables a series of interesting E-configured vinylarenes (confirmed by X-ray crystal-structure analysis)… read more here.
Keywords: alkyl substituted; nickel catalysed; olefination; catalysed direct ... See more keywords
The salt-free nickel-catalysed α-allylation reaction of ketones with allyl alcohol and diallylether
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DOI: 10.1039/c9gc03619a
Abstract: The nickel-catalysed α-allylation of ketones with allyl alcohol and diallylether has been performed under neutral conditions. As no base is involved, the products are synthesized without salts as side products. The dppf/Ni(cod)2 catalytic system in… read more here.
Keywords: catalysed allylation; allyl alcohol; ketones allyl; nickel catalysed ... See more keywords
Sequential olefination–dimerisation of benzylic dithioacetals by the nickel-catalysed reaction with methyl Grignard or zinc reagent
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DOI: 10.1039/d2ra00841f
Abstract: Products of main group elements from cross-coupling reactions have been shown to serve as Lewis acids, mediating further reactions of organic coupling products. Thus, the nickel-catalysed olefination of benzylic dithioacetal with MeMgI in benzene in… read more here.
Keywords: reagent; nickel catalysed; grignard; olefination dimerisation ... See more keywords
Nickel-catalysed diversification of phosphine ligands by formal substitution at phosphorus
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02496a
Abstract: We report a diversification strategy that enables the direct substituent exchange of tertiary phosphines. Alkylated phosphonium salts, prepared by standard alkylation of phosphines, are selectively dearylated in a nickel-catalysed process to access alkylphosphine products via… read more here.
Keywords: nickel catalysed; substitution phosphorus; diversification; formal substitution ... See more keywords
Structural authentication of intermediates of mechanistic significance in palladium- and nickel-catalysed cross-couplings: case studies.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00882g
Abstract: This article examines a selection of case studies that highlight key strategies that have enabled the structural authentication of important species that shed light on fundamental on-cycle intermediates in palladium- and nickel-catalysed C-C, C-N, and… read more here.
Keywords: palladium nickel; catalysed cross; nickel catalysed; case studies ... See more keywords
Nickel-Catalysed Allylboration of Aldehydes
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DOI: 10.1055/s-0039-1690091
Abstract: A nickel catalyst for the allylboration of aldehydes is reported, facilitating the preparation of homoallylic alcohols in high diastereoselectivity. The observed diastereoselectivities and NMR experiments suggest that allylation occurs through a well-defined six-membered transition state,… read more here.
Keywords: allylboration; nickel catalysed; catalysed allylboration; allylboration aldehydes ... See more keywords