Allylboronates from Vinyl Triflates and α-Chloroboronates by Reductive Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c01683
Abstract: Allylboronates are unique building blocks widely used in organic synthesis, but the construction of cyclic allylboranates remains a challenging subject. We demonstrate here a mild and efficient access to this type of compound through the… read more here.
Keywords: allylboronates vinyl; triflates chloroboronates; nickel catalysis; chloroboronates reductive ... See more keywords
Redox-Neutral 1,4-Dicarbonfunctionalization of 1,3-Butadiene by Merging Photoredox and Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04060
Abstract: The diverse functionalization of 1,3-butadiene provides wide applicability toward the synthesis of abundant and useful allylic compounds. Here, we describe a three-component and redox-neutral assembly of readily available C═X compounds, 1,3-butadiene, and various nucleophiles by… read more here.
Keywords: butadiene; nickel catalysis; merging photoredox; photoredox nickel ... See more keywords
Construction of a Pentacyclic Framework Enabled by Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04228
Abstract: We present a novel nickel-catalyzed reaction of indole-tethered 2-alkynylphenol esters with various (hetero)aryl boronic acids, resulting in the synthesis of diversely functionalized pentacyclic benzofurocyclohepta[b]indole derivatives. This unprecedented cascade reaction involves the arylative cyclization of alkynes,… read more here.
Keywords: nickel catalysis; construction pentacyclic; framework enabled; enabled nickel ... See more keywords
ART─An Amino Radical Transfer Strategy for C(sp2)-C(sp3) Coupling Reactions, Enabled by Dual Photo/Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03220
Abstract: Introducing the novel concept of amino radical transfer (ART) enables the use of easily accessible and commercially available alkyl boronic esters as cross-coupling partners for aryl halides in dual photoredox/nickel catalysis mediated by visible light.… read more here.
Keywords: radical transfer; sp2 sp3; nickel catalysis; amino radical ... See more keywords
Site- and Stereoselective Synthesis of Alkenyl Chlorides by Dual Functionalization of Internal Alkynes via Photoredox/Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c02748
Abstract: Herein, we report a redox-neutral and atom-economical protocol to synthesize valuable alkenyl chlorides from unactivated internal alkynes and abundant organochlorides via photoredox and nickel catalysis. This protocol enables the site- and stereoselective addition of organochlorides… read more here.
Keywords: internal alkynes; nickel catalysis; via photoredox; site stereoselective ... See more keywords
Deoxygenation of Ethers To Form Carbon-Carbon Bonds via Nickel Catalysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b02326
Abstract: In this article a successful protocol was developed to construct carbon-carbon bonds by the extrusion of the O atom of ethers via nickel catalysis in the presence of reductants. This methodology is featured as a… read more here.
Keywords: carbon bonds; nickel catalysis; carbon; carbon carbon ... See more keywords
Intercepting fleeting cyclic allenes with asymmetric nickel catalysis
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2701-2
Abstract: Strained cyclic organic molecules, such as arynes, cyclic alkynes and cyclic allenes, have intrigued chemists for more than a century with their unusual structures and high chemical reactivity 1 . The considerable ring strain (30–50… read more here.
Keywords: nickel catalysis; absolute stereochemistry; allene; asymmetric nickel ... See more keywords
Direct acylation and alkynylation of hydrocarbons via synergistic decatungstate photo-HAT/nickel catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04408k
Abstract: Herein, we describe a protocol for the direct and selective acylation and alkynylation of the C(sp3)-H bonds of saturated hydrocarbons by synergistic decatungstate photo-HAT and nickel catalysis. This method, using cheap and easy-to-synthesize TBADT as… read more here.
Keywords: decatungstate photo; synergistic decatungstate; nickel catalysis; hat nickel ... See more keywords