Biochemical characterization of mismatch-binding protein MutS1 and nicking endonuclease MutL from a euryarchaeon Methanosaeta thermophila.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.01.005
Abstract: In eukaryotes and most bacteria, the MutS1/MutL-dependent mismatch repair system (MMR) corrects DNA mismatches that arise as replication errors. MutS1 recognizes mismatched DNA and stimulates the nicking endonuclease activity of MutL to incise mismatch-containing DNA.… read more here.
Keywords: endonuclease; nicking endonuclease; muts1 mutl; mutl ... See more keywords
Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of p53 gene based on nicking endonuclease-assisted target recycling and rolling circle amplification
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106461
Abstract: Abstract Tumor suppressor p53 gene is one vital anticancer gene that plays critical role in the prevention, diagnosis, and prognosis evaluation of cancers. Specific recognition and sensitive detection of p53 gene is important for early… read more here.
Keywords: p53 gene; nicking endonuclease; gene; biosensor ... See more keywords