Low doses of niclosamide and quinacrine combination yields synergistic effect in melanoma via activating autophagy-mediated p53-dependent apoptosis.
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DOI: 10.1016/j.tranon.2022.101425
Abstract: Malignant melanoma is a highly aggressive, malignant, and drug-resistant tumor. It lacks an efficient treatment approach. In this study, we developed a novel anti-melanoma strategy by using anti-tapeworm drug niclosamide and anti-malarial drug quinacrine, and… read more here.
Keywords: low doses; niclosamide quinacrine; melanoma; apoptosis ... See more keywords