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Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081109
Abstract: Inhibition of Plasmodium falciparum nicotinamidase could represent a potential antimalarial since parasites require nicotinic acid to successfully recycle nicotinamide to NAD+, and importantly, humans lack this biosynthetic enzyme. Recently, mechanism-based inhibitors of nicotinamidase have been…
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Keywords:
plasmodium falciparum;
nicotinamidase novel;
nicotinamidase;
novel antimalarial ... See more keywords