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Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling

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3 Published in 2022 at "iScience"

DOI: 10.1016/j.isci.2022.103932

Abstract: Summary Nicotinamide (NAM) shapes T cell responses but its precise molecular mechanism of action remains elusive. Here, we show that NAM impairs naive T cell effector transition but also effector T cells themselves. Although aerobic… read more here.

Keywords: effector; cell; cell responses; breaks effector ... See more keywords