Catalytic Promiscuity of Horseradish Peroxidase: Aerobic Oxidative Regeneration of Oxidized Nicotinamide Cofactors
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DOI: 10.1002/cctc.202300330
Abstract: NAD(P)+ regeneration is of great importance for dehydrogenase (DH)‐catalyzed oxidations. In this work, we report horseradish peroxidase (HRP)‐catalyzed aerobic oxidation of the reduced nicotinamide cofactors, including natural and non‐natural ones, into the oxidized form at… read more here.
Keywords: regeneration; nicotinamide cofactors; horseradish peroxidase; promiscuity horseradish ... See more keywords
Bioinspired cooperative photobiocatalytic regeneration of oxidized nicotinamide cofactors for catalytic oxidations.
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DOI: 10.1002/cssc.202100184
Abstract: Inspired by water-forming NAD(P)H oxidases, a cooperative photobiocatalytic system was designed to aerobically regenerate the oxidized nicotinamide cofactors in this work. Photocatalysts enabled NAD(P)H oxidation to the oxidized forms with O 2 under irradiation of… read more here.
Keywords: catalytic oxidations; nicotinamide cofactors; system; oxidized nicotinamide ... See more keywords
Engineering Isopropanol Dehydrogenase for Efficient Regeneration of Nicotinamide Cofactors
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DOI: 10.1128/aem.00341-22
Abstract: Oxidoreductases represent one group of the most important biocatalysts for synthesis of various chiral synthons. However, their practical application was hindered by the expensive nicotinamide cofactors used. ABSTRACT Isopropanol dehydrogenase (IPADH) is one of the… read more here.
Keywords: regeneration; nicotinamide cofactors; cofactor; isopropanol dehydrogenase ... See more keywords
The Auxiliary NADH Dehydrogenase Plays a Crucial Role in Redox Homeostasis of Nicotinamide Cofactors in the Absence of the Periplasmic Oxidation System in Gluconobacter oxydans NBRC3293
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DOI: 10.1128/aem.02155-20
Abstract: Nicotinamide cofactors NAD+ and NADP+ mediate redox reactions in metabolism. Gluconobacter oxydans, a member of the acetic acid bacteria, oxidizes glucose incompletely in the periplasmic space—outside the cell. This incomplete oxidation of glucose is independent… read more here.
Keywords: periplasmic oxidation; oxidation; nicotinamide cofactors; glucose ... See more keywords