The impact of perinatal nicotine exposure on fetal lung development and subsequent respiratory morbidity
Sign Up to like & getrecommendations! Published in 2019 at "Birth Defects Research"
DOI: 10.1002/bdr2.1595
Abstract: Maternal smoking during pregnancy remains as a significant public health crisis as it did decades ago. Although its prevalence is decreasing in high‐income countries, it has worsened globally, along with a concerning emergence of electronic‐cigarette… read more here.
Keywords: nicotine exposure; exposure; perinatal nicotine; respiratory morbidity ... See more keywords
Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice
Sign Up to like & getrecommendations! Published in 2020 at "Birth Defects Research"
DOI: 10.1002/bdr2.1840
Abstract: Maternal nicotine exposure during gestation and lactation adversely affect lung development of their children. High‐mobility group box 1 (HMGB1) is the encoded non‐histone, nuclear DNA‐binding protein that regulates transcription, and is involved in organization of… read more here.
Keywords: hmgb1 rage; rage expression; nicotine exposure; exposure ... See more keywords
Chronic nicotine exposure attenuates the effects of Δ9‐tetrahydrocannabinol on anxiety‐related behavior and social interaction in adult male and female rats
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1375
Abstract: Anxiogenic and anxiolytic effects of cannabinoids are mediated by different mechanisms, including neural signaling via cannabinoid receptors (CBRs) and nicotinic cholinergic receptors (nAChRs). This study examined the effects of prior nicotine (the psychoactive component in… read more here.
Keywords: exposure attenuates; effects tetrahydrocannabinol; nicotine exposure; chronic nicotine ... See more keywords
Influence of developmental nicotine exposure on serotonergic control of breathing‐related motor output
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22866
Abstract: Serotonin plays an important role in the development of brainstem circuits that control breathing. Here, we test the hypothesis that developmental nicotine exposure (DNE) alters the breathing‐related motor response to serotonin (5HT). Pregnant rats were… read more here.
Keywords: breathing related; developmental nicotine; frequency; control breathing ... See more keywords
Nicotine exposure through breastfeeding affects brain‐derived neurotrophic factor and synaptic proteins levels in the brain of stressed adult female mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10227
Abstract: Nicotine has been used during pregnancy and lactation as a tobacco harm reduction strategy. However, it is unclear whether nicotine exposure during a critical development period negatively impacts stress responses in adulthood. This study investigated… read more here.
Keywords: mice; nicotine exposure; brain; synaptic proteins ... See more keywords
The impact of tobacco chemicals and nicotine on placental development
Sign Up to like & getrecommendations! Published in 2020 at "Prenatal Diagnosis"
DOI: 10.1002/pd.5660
Abstract: Despite decades of messages warning about the dangers of tobacco use in pregnancy, 10% to 15% of pregnant women continue to smoke. Furthermore, an increased popularity of electronic nicotine delivery systems (ENDS) over the past… read more here.
Keywords: tobacco; tobacco chemicals; nicotine exposure; impact tobacco ... See more keywords
Chronic Nicotine Exposure Minimally Affects Rat Supraspinatus Tendon Properties and Bone Microstructure.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of biomedical engineering"
DOI: 10.1007/s10439-020-02667-x
Abstract: Cigarette smoking is the largest cause of preventable deaths, and a known risk factor for musculoskeletal issues including rotator cuff tendon tears. Tendon degeneration is believed to be due in part to changes in tendon… read more here.
Keywords: bone microstructure; nicotine exposure; rat supraspinatus; supraspinatus tendon ... See more keywords
Maternal nicotine exposure has severe cross-generational effects on offspring behavior
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.04.033
Abstract: Our previous studies showed that paternal nicotine exposure can lead to hyperactivity in the offspring. Nevertheless, the cross-generational effects of maternal and biparental nicotine exposure remain unclear. In this study, female and male mice were… read more here.
Keywords: generational effects; nicotine exposure; maternal nicotine; exposure ... See more keywords
Adolescent and adult nicotine exposure differentially impacts oral nicotine and oral saccharin self-administration in mice
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.07.019
Abstract: HighlightsAdolescent nicotine exposure increased saccharin reinforcement in adulthood.Adult nicotine re‐exposure biased the sensitivity towards nicotine reward.Both adolescent and adult nicotine exposure increased impulsive responding.Adolescent and adult nicotine experience activated distinct behavioral mechanisms.These mechanisms acted in… read more here.
Keywords: oral nicotine; saccharin; nicotine exposure; exposure ... See more keywords
Perinatal nicotine exposure impairs learning of a skilled forelimb reaching task in male but not female adult mice
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.04.007
Abstract: Developmental tobacco or nicotine exposure is associated with various adverse outcomes in human and preclinical studies, respectively. For example, perinatal nicotine exposure in mice causes morphologic changes in neurons across sensory and motor cortices and… read more here.
Keywords: seed; task; male female; nicotine exposure ... See more keywords
Protective effect of electro-acupuncture at maternal different points on perinatal nicotine exposure-induced pulmonary dysplasia in offspring based on HPA axis and signal transduction pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.09.145
Abstract: Perinatal nicotine exposure can not only lead to lung dysplasia in offspring, but also cause epigenetic changes and induce transgenerational asthma. Previous studies have shown that electro-acupuncture (EA) applied to "Zusanli" (ST 36) can improve… read more here.
Keywords: dysplasia offspring; nicotine exposure; perinatal nicotine; pulmonary dysplasia ... See more keywords