Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia
Sign Up to like & getrecommendations! Published in 2017 at "Psychopharmacology"
DOI: 10.1007/s00213-017-4794-3
Abstract: BackgroundNicotine improves attention and processing speed in individuals with schizophrenia. Few studies have investigated the effects of nicotine on cognitive control. Prior functional magnetic resonance imaging (fMRI) research demonstrates blunted activation of dorsal anterior cingulate… read more here.
Keywords: nicotine induced; response; cingulate cortex; activation ... See more keywords
Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson’s Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism
Sign Up to like & getrecommendations! Published in 2018 at "Neurotoxicity Research"
DOI: 10.1007/s12640-018-9931-1
Abstract: Parkinson’s disease (PD) is characterized by the degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNpc). Clinical and experimental evidence suggest that the activation of the nicotinic acetylcholine receptor (nAChR) could be… read more here.
Keywords: nicotine; nicotine induced; labile iron; parkinson disease ... See more keywords
Varenicline rescues nicotine-induced decrease in motivation for sucrose reinforcement
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112887
Abstract: Varenicline is one of the top medications used for smoking cessation and is often prescribed before termination of nicotine use. The effect of this combined nicotine and varenicline use on the reward system and motivation… read more here.
Keywords: varenicline rescues; nicotine induced; varenicline; nicotine varenicline ... See more keywords
An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103874
Abstract: We herein report the design, synthesis, and functional impact of an okadaic acid (OA) small analogue, ITH12680, which restores the activity of phosphoprotein phosphatase 2A (PP2A), whose deficient activity has been implicated in nicotine-mediated tumor… read more here.
Keywords: pp2a activity; nicotine induced; resistance; cell ... See more keywords
Nicotine-induced C-shape movements in planarians are reduced by antinociceptive drugs: Implications for pain in planarian paroxysm etiology?
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.1016/j.brainres.2021.147770
Abstract: C-shapes are stereotyped movements in planarians that are elicited by diverse stimuli (e.g. acidity, excitatory neurotransmitters, psychostimulants, and pro-convulsants). Muscle contraction and seizure contribute to the expression of C-shape movements, but a causative role for… read more here.
Keywords: shape movements; movements planarians; nicotine; nicotine induced ... See more keywords
Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108929
Abstract: Fatty liver is the hepatic consequence of chronic insulin resistance (IR) and related syndromes. It is mostly accompanied by inflammatory and oxidative molecules. Increased activity of xanthine oxidase (XO) exerts both inflammatory and oxidative effects… read more here.
Keywords: xanthine oxidase; nicotine induced; acetate; sodium acetate ... See more keywords
Inhibition of N-acylethanolamine acid amidase reduces nicotine-induced dopamine activation and reward
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.11.013
Abstract: &NA; Tobacco smoke is the leading preventable cause of death in the world and treatments aimed to increase success rate in smoking cessation by reducing nicotine dependence are sought. Activation of peroxisome proliferator‐activated receptor‐alpha (PPAR&agr;)… read more here.
Keywords: nicotine; ppar agr; nicotine induced; dopamine ... See more keywords
Nicotine-induced and D1-receptor-dependent dendritic remodeling in a subset of dorsolateral striatum medium spiny neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.05.036
Abstract: Nicotine is one of the most addictive substances known, targeting multiple memory systems, including the ventral and dorsal striatum. One form of neuroplasticity commonly associated with nicotine is dendrite remodeling. Nicotine-induced dendritic remodeling of ventral… read more here.
Keywords: nicotine; nicotine induced; spiny neurons; striatum ... See more keywords
Multigenerational nicotine exposure affects offspring nicotine metabolism, nicotine-induced hypothermia, and basal corticosterone in a sex-dependent manner.
Sign Up to like & getrecommendations! Published in 2021 at "Neurotoxicology and teratology"
DOI: 10.1016/j.ntt.2021.106972
Abstract: Parental nicotine exposure can impact phenotypes in unexposed offspring. Our laboratory recently published data showing that nicotine reward and hippocampal gene expression involved in stress pathways were perturbed in F1 offspring of male C57BL/6J mice… read more here.
Keywords: nicotine; corticosterone; nicotine induced; nicotine exposure ... See more keywords
Protective effects of quercetin on nicotine induced oxidative stress in ‘HepG2 cells’
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2017.1344338
Abstract: Abstract Nicotine is a natural component of tobacco plants and is responsible for the addictive properties of tobacco. Nicotine has been recognized to result in oxidative stress by inducing the generation of reactive oxygen species… read more here.
Keywords: nicotine; nicotine induced; hepg2 cells; hepg2 ... See more keywords
Influence of alpha-lipoic acid on nicotine-induced lung and liver damage in experimental rats.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0366
Abstract: Nicotine mediates some of the injurious effects caused by consuming tobacco products. This work aimed at investigating the defensive role of alpha-lipoic acid (ALA) with its known antioxidant and antiinflammatory effect in nicotine-induced lung and… read more here.
Keywords: liver damage; nicotine induced; lung liver;