Complete Genome Sequence of Alcaligenes Faecalis Strain JQ135, a Bacterium Capable of Efficiently Degrading Nicotinic Acid
Sign Up to like & getrecommendations! Published in 2018 at "Current Microbiology"
DOI: 10.1007/s00284-018-1486-0
Abstract: Nicotinic acid (NA), known as vitamin B3, is ubiquitous in nature and plays an important role in living organisms. The microbial catabolism of NA is highly diverse. However, the NA degradation by Alcaligenes faecalis strains… read more here.
Keywords: genome sequence; alcaligenes faecalis; complete genome; sequence ... See more keywords
A novel nitrilase from Ralstonia eutropha H16 and its application to nicotinic acid production
Sign Up to like & getrecommendations! Published in 2017 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-017-1787-x
Abstract: A novel aliphatic nitrilase, REH16, was found in Ralstonia eutropha H16 and overexpressed in Escherichia coli BL21(DE3), and its enzymatic properties were studied. The temperature and pH optima were 37 °C and 6.6, respectively, and the… read more here.
Keywords: ralstonia eutropha; nitrilase; cyanopyridine; eutropha h16 ... See more keywords
Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatments
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacokinetics and Pharmacodynamics"
DOI: 10.1007/s10928-017-9512-6
Abstract: Nicotinic acid (NiAc) is a potent inhibitor of adipose tissue lipolysis. Acute administration results in a rapid reduction of plasma free fatty acid (FFA) concentrations. Sustained NiAc exposure is associated with tolerance development (drug resistance)… read more here.
Keywords: exposure; ffa; resistance; nicotinic acid ... See more keywords
Study on the Interaction of Nicotinic Acid with l-Phenylalanine in Buffer Solution by Heat Capacity Measurements at Various Temperatures
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Solution Chemistry"
DOI: 10.1007/s10953-017-0570-6
Abstract: The interaction between nicotinic acid (NA) and l-phenylalanine (Phe) was studied in aqueous phosphate buffer solutions (pH = 7.35) by differential scanning calorimetry. Heat capacities of nicotinic acid–buffer, l-phenylalanine–buffer, and nicotinic acid–l-phenylalanine–buffer mixtures were determined at (283.15,… read more here.
Keywords: heat; acid phenylalanine; nicotinic acid; buffer ... See more keywords
Thermochemical Properties of Dissolution of Nicotinic Acid C6H5NO2(s) in Aqueous Solution
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DOI: 10.1007/s10953-017-0607-x
Abstract: Nicotinic acid (also known as niacin) was recrystallized from anhydrous ethanol. X-ray crystallography was applied to characterize its crystal structure. The crystal belongs to the monoclinic system, space group P2(1)/c. The crystal cell parameters are… read more here.
Keywords: text; aqueous solution; nicotinic acid; text text ... See more keywords
Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113842
Abstract: SARM1 is an inducible NAD+ hydrolase that is the central executioner of pathological axon loss. Recently, we elucidated the molecular mechanism of SARM1 activation, demonstrating that SARM1 is a metabolic sensor regulated by the levels… read more here.
Keywords: nad hydrolase; sarm1; nicotinic acid; allosteric site ... See more keywords
Synthesis, optical and magnetic study of nicotinic acid ligand lanthanum, neodymium and terbium complexes
Sign Up to like & getrecommendations! Published in 2021 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2021.120561
Abstract: Abstract In this work, three rare earth complexes, namely, [La(cpna)2·2H2O]n (1), [Nd(Hcpna)(cpna)•3H2O]n (2) and [Tb(Hcpna)(cpna)•3H2O]n (3) have been synthesized by solvothermal method based on 5-(4-carboxyphenoxy)nicotinic acid ligand (H2cpna) and rare earth metal ions La3+, Nd3+… read more here.
Keywords: optical magnetic; acid ligand; synthesis optical; nicotinic acid ... See more keywords
Sonochemical synthesis of 2-substituted nicotinic acid ethyl ester derivatives: Their in vitro and in silico evaluation against SIRT1
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131069
Abstract: Abstract Based on the initial docking studies of a representative compound in silico the evaluation of SIRT1 inhibitory potential of 2-substituted nicotinic acid ethyl ester derivatives was undertaken in vitro. A sonochemical method was developed… read more here.
Keywords: acid ethyl; ethyl ester; ester derivatives; nicotinic acid ... See more keywords
Equilibrium and Thermodynamic Studies on Reactive Extraction of Nicotinic Acid Using a Biocompatible Extraction System
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemical & Engineering Data"
DOI: 10.1021/acs.jced.7b00457
Abstract: The separation of organic compounds using reactive extraction (combination of extractant + solvent system) has a great potential in the near future but limits its application in the extractive fermentation system because of the toxicity… read more here.
Keywords: extraction; system; acid using; reactive extraction ... See more keywords
Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00773
Abstract: Pyridomycin is a potent antimycobacterial natural product by specifically inhibiting InhA, a clinically validated antituberculosis drug discovery target. Pyridyl moieties of pyridomycin play an essential role in inhibiting InhA by occupying the reduced form of… read more here.
Keywords: nadc homologue; nicotinic acid; acid; formation ... See more keywords
Metal ion coordination enhancing quantum efficiency of ligand phosphorescence in a double-stranded helical chain coordination polymer of Pb2+ with nicotinic acid.
Sign Up to like & getrecommendations! Published in 2018 at "Dalton transactions"
DOI: 10.1039/c8dt03589j
Abstract: A new 1D phosphorescence coordination polymer (CP) [Pb2O(C6H4NO2)2]n (1; C6H4NO2 = nicotinate) was synthesized by a solvothermal reaction and PbO was used as a Pb(ii) source instead of traditional Pb(ii) salts. This remarkably thermal-stable CP… read more here.
Keywords: coordination; coordination polymer; phosphorescence; nicotinic acid ... See more keywords